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Questions and answers for HTHSCI 3I03: T cell Regulation and Memory $8.00   Add to cart

Exam (elaborations)

Questions and answers for HTHSCI 3I03: T cell Regulation and Memory

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  • HTHSCI 3I03
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  • HTHSCI 3I03

Questions and answers for HTHSCI 3I03: T cell Regulation and Memory

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  • October 3, 2024
  • 9
  • 2024/2025
  • Exam (elaborations)
  • Questions & answers
  • HTHSCI 3I03
  • HTHSCI 3I03
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Describe the process of TCR degeneracy.


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, Upon infection with pathogen 1, both T cells specific for pathogen 1 and
auto-reactive T cells that recognize pathogen 1 proliferate. During
contraction, the number of both decreases. Under normal conditions once
infection is cleared, peripheral tolerance persists and only T cells specific
for pathogen 1 are present. These specific T cells allow memory of the
pathogen.




Why must TCR degeneracy occur?


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T cells compete for nutrients, so T cells that are not actively engaged in the
immune response are disadvantaged simply because they are not needed.




What T cells are actively deleted after resolution of infection?


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Auto-reactive T cells




How many peripheral T cells express 2 TCRs?


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Estimated 30%

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