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Questions and answers for HTHSCI 3I03: CD4+ T cells
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Questions and answers for HTHSCI 3I03: CD4+ T cells
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1-29 of 29Interleukin
Cytokines produced by leukocytes
, How do CD4+ T cells develop into a subtype?
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Acquire memory of original exposure and try to recreate original local
environment upon subsequent detection by producing the same cytokines
What cytokines are produced by dendritic cells upon interaction with viruses and
some bacteria and what effect does this have?
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Viruses and some bacteria induce IL-12 secretion by dendritic cells that
can activate NK cells to produce IFN-y. Naive CD4+ T cells activated in the
presence of these cytokines differentiate into TH1 cells.
What defines the subtype of CD4+ T cells?
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The CD4+ T cell subtype (i.e. polarity) is defined by the cytokines (i.e. Signal
3) present at the time of naïve CD4+ T cell priming, which are similar to
cytokines that are produced by the differentiated CD4+ T cells
Treg
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