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Questions and answers for HTHSCI 3I03: Activation of Naive T cell and Killer CD8 $8.00   Add to cart

Exam (elaborations)

Questions and answers for HTHSCI 3I03: Activation of Naive T cell and Killer CD8

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  • HTHSCI 3I03

Questions and answers for HTHSCI 3I03: Activation of Naive T cell and Killer CD8

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  • October 3, 2024
  • 14
  • 2024/2025
  • Exam (elaborations)
  • Questions & answers
  • HTHSCI 3I03
  • HTHSCI 3I03
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codersimon
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What signals do naive T cells require to become fully activated?


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1. TCR binding to specific MHC/peptide
2. Co-stimulatory receptor binding of co-stumulatory ligands

, What cell type is required for proper clean apoptosis to occur?


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Macrophages to phagocytose the components of the dissolved cell




In what two ways can a cell die?


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1. Necrosis: messy cell death due to injury or disease (ex: following trauma
or infection)
2. Apoptosis: organized programmed cell death (ex: removal of cells
during development)




What interaction activates the co-stimulatory pathway?


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CD28 with CD80 or CD86




Describe the killing path of CD8 T cells.


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1. Cytotoxic CD8 T cell recognizes virus-infected cell with MHC I and
antigen specific for TCR
2. CD8 T cell programs first target cell to die

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