100% satisfaction guarantee Immediately available after payment Both online and in PDF No strings attached
logo-home
Previously searched by you
Previously searched by you
logo
BIOCHEMISTRY CHAPTER 28 FATTY ACID SYNTHESIS Questions and Answers $13.49   Add to cart
Quickly navigate to
Preview
  2.  
  3. ASID
  4.  
  5. ASID

Exam (elaborations)

BIOCHEMISTRY CHAPTER 28 FATTY ACID SYNTHESIS Questions and Answers
 7 views  0 purchase
  • Course
  • ASID
  • Institution
  • ASID

BIOCHEMISTRY CHAPTER 28 FATTY ACID SYNTHESIS Questions and Answers WHAT ARE THE RAW MATERIALS FOR FATTY ACID SYNTHESIS AND HOW ARE THEY OBTAINED? ACETYL COA IS THE BASIC SUBSTRATE IT IS TRANSPORTED OUT OF THE MITOCHINDRIA IN THE FORM OF CITRATE. AFTER THE FORMATION OF ACETYL COA, THE RESULTING ...

[Show more]

Preview 2 out of 5  pages

Document information

  • October 2, 2024
  • 5
  • 2024/2025
  • Exam (elaborations)
  • Questions & answers

Subjects

  • biochemistry chapter 28 fatty acid synthesis quest
  • what are the raw materials for fatty acid synthesi
  • how are fatty acid synthesis and degradation coord

Written for

  • ASID
  • ASID

Seller

avatar-seller
Pogba119

Reviews received

Content preview

BIOCHEMISTRY CHAPTER 28 FATTY
ACID SYNTHESIS Questions and
Answers
WHAT ARE THE RAW MATERIALS FOR FATTY ACID SYNTHESIS AND HOW ARE
THEY OBTAINED? - answer ACETYL COA IS THE BASIC SUBSTRATE
IT IS TRANSPORTED OUT OF THE MITOCHINDRIA IN THE FORM OF CITRATE.
AFTER THE FORMATION OF ACETYL COA, THE RESULTING OXALOACETATE IS
TRANSPORTED BACK INTO THE MITOCHONDRIA WITH A CONCOMITANT
FORMATION OF NADPH, THE REDUCING POWER FOR FA SYNTHESIS.
ADDITIONAL NADPH CAN BE GENERATED BY THE PPP. MAOLONYL COA , THE
ULTIMATE SUBSTRATE FOR FA SYNTHESIS IS FORMED BY THE
CARBOXYLATION OF ACETYL COA.

HOW ARE FATTY ACID SYNTHESIS AND DEGRADATION COORDINATED? -
answer MALONYL COA, THE SUBSTRATE FOR FA SYNTHESIS INHIBITS CAT I,
THUS PREVENTING THE TRANSPORT OF FA INTO MITOCHONDRIA FOR
DEGRADATION. PALMITOYL COA INHIBITS ACETYL COA CARBOXYLASE, THE
TRANSPORT OF CITRATE INTO THE CYTOPLASM, AND GLUCOSE6-PHOSPHATE
DEHYDROGENASE, THE CONTROLLING ENZYME OF THE PPP.

WHAT IS THE OVERALL STOICHIOMETRY FOR THE SYNTHESIS OF PALMITATE
FROM ACETYL COA? - answer 8 ACETYL COA + 7 ATP + 14NADPH --->
PALMITATE + 14 NADP + +8 COA + 6 H2O + 7 ADP + 7Pi

WHAT ARE THE THREE REACTIONS THAT ALLOW THE CONVERSION OF
CYTOPLASMIC NADH INTO NADPH?
WHAT ENZYMES ARE REQUIRED?
WHAT IS THE SUM OF THE 3 REACTIONS? - answer FIRST:
OXALOACETATE + NADH + H+ <---> MALATE + NAD+
(CATALYZED BY CYTOPLASMIC MALATE DEHYDROGENASE)
SECOND:
MALATE + NADP+ ---> PYRUVATE + CO2 + NADPH
(CATALYZED BY MALIC ENZYME)
THIRD:
PYRUVATE + CO2 + ATP + H2O ---> OXALOACETATE + ADP + Pi + 2H+
(CATALYZED BY PYRUVATE DECARBOXYLASE)
NET:
NADP+ + NADH + ATP + H2O---> NADPH + NAD+ + ADP + Pi + H+

, WHAT IS THE COMMITTED STEP IN FA SYNTHESIS AND WHICH ENZYME
CATALYZES IT? - answer THE FORMATION OF MALONYL COA FROM ACETYL
COA BY ACETYL COA CARBOXYLASE.

ATP-CITRATE LYASE - answer GENERATES CYTOPLASMIC ACETYL COA

MALIC ENZYME - answer HELPS TO GENERATE NADPH FROM NADH

MALONYL COA - answer ACTIVATED ACETYL COA

ACETYL COA CARBOXYLASE - answer CATALYZES THE COMMITTED STEP IN
FA SYNTHESIS

ACYL CARRIER PROTEIN - answer MOLECULE ON WHICH FA ARE
SYNTHESIZED

B-KETOACYL SYNTHASE - answer CATALYZES THE REACTION OF ACETYL
COA AND MAOLONYL COA

PALMITATE - answer THE END PRODUCT OF FA SYNTHASE

EICOSANOIDS - answer FA CONTAINING 20 CARBON ATOMS

ARACHIDONATE - answer A PRECURSOR OF PROSTAGLANDINS

AMP-DEPENDENT PROTEIN KINASE - answer INACTIVATES ACETYL COA
CARBOXYLASE

WRITE A BALANCED EQUATION FOR THE SYNTHESIS OF MYRISTATE. - answer
7 ACETYL COA + 6 ATP + 12 NADPH + 12H+ ---> MYRISTATE + 7 COA + 6 ADP + 6
Pi + 12 NADP+ + 5H2O

HOW MANY MOLECULES OF ATP AND NADPH ARE REQUIRED TO SYNTHESIZE
LAURIC ACID? - answer 6 ACETYL COA:
1 BECOMES 2 CARBONS FARTHEST FROM ACID END
5 GET CONVERTED INTO MALONYL COA
EACH MALONYL REQUIRES 1 ATP
5 ATP ARE REQUIRED
EACH ELONGATION REQUIRES 2 NADPH
10 NADPH ARE REQUIRED

ARRANGE IN PROPER ORDER

DEHYDRATION
CONDENSATION
RELEASE OF C16 FA

The benefits of buying summaries with Stuvia:

Guaranteed quality through customer reviews

Guaranteed quality through customer reviews

Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.

Quick and easy check-out

Quick and easy check-out

You can quickly pay through credit card or Stuvia-credit for the summaries. There is no membership needed.

Focus on what matters

Focus on what matters

Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!

Frequently asked questions

What do I get when I buy this document?

You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.

Satisfaction guarantee: how does it work?

Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.

Who am I buying these notes from?

Stuvia is a marketplace, so you are not buying this document from us, but from seller Pogba119. Stuvia facilitates payment to the seller.

Will I be stuck with a subscription?

No, you only buy these notes for $13.49. You're not tied to anything after your purchase.

Can Stuvia be trusted?

4.6 stars on Google & Trustpilot (+1000 reviews)

72042 documents were sold in the last 30 days

Founded in 2010, the go-to place to buy study notes for 14 years now

Start selling
$13.49
  • (0)
  Add to cart