NURS 8022 PATHO EXAM 1 ACTUAL
EXAM 2024 -2025 ACTUAL EXAM
COMPLETE 400 QUESTIONS WITH
DETAILED VERIFIED ANSWERS (100%
CORRECT ANSWERS) /ALREADY
GRADED A+
An end plate potential; which will normally initiate an
AP if the local spread of current is sufficient to open
voltage sodium channels. - ....ANSWER...Opening of
the nACh receptor channels produces:
Block nicotinic Ach channels by competing for AcH
binding site
reduces ampltitude of end plate potential therefore
no AP - ....ANSWER...Inhibitor drug: Curariform drugs
(D-turbocurarie)
Decreases the release of AcH from nerve terminals
,Insufficient stimulus to initiate an AP. -
....ANSWER...Inhibitor drug: Botulinum toxin
bind and activate nicotinic AcH receptors
Not destroyed by AcHE- prolonged effect -
....ANSWER...AcH like drugs (Methacholine,
carbachol, nicotine)
inactivate acetylcholinesterace; can treat MG -
....ANSWER...Anti AcHe drugs (neostigmine,
physostigmine, diisopropyl flurophosphate or "nerve
gas")
Autoimmune disorder that attacks Ach nicotinic
cholinergic receptors at NM junction. This results in
weakness in face and legs. Treatments include anti-
cholinesterases and immunosuppresive drugs. -
....ANSWER...Myesthenia Gravis
is a functional contracting unit of the muscle fiber -
....ANSWER...Sarcomere
myosin - ....ANSWER...Thick filaments
, Actin, tropomyosin and troponin - ....ANSWER...Thin
filaments
attaches troponin complex to tropomyosin -
....ANSWER...Troponin T
Along with tropomyosin inhibits the interaction of
actin and myosin by covering myosin binding site of
actin - ....ANSWER...Troponin I
is a Ca2+ binding protein that plays central role in
the initiation of contraction - ....ANSWER...Troponin C
CALCIUM! - ....ANSWER...What is important in
excitation contraction coupling?
As long as intracellular Ca2+ is low, cross bridge
cycling cannot occur and muscle relaxes -
....ANSWER...Relaxation in muscle contraction
The intracellular Ca2+ contraction never returns to
the low levels that exist during relaxation; results in
continued binding of Ca2+ to troponin C -
....ANSWER...Tetanus
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