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TEST BANK Katzung's Basic and Clinical Pharmacology, 16th Edition by Todd W. Vanderah, Chapters 1 – 66 A+ TEST BANK Katzung's Basic and Clinical Pharmacology, 16th Edition by Todd W. Vanderah, Chapters 1 – 66 A+ $12.99   Add to cart

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TEST BANK Katzung's Basic and Clinical Pharmacology, 16th Edition by Todd W. Vanderah, Chapters 1 – 66 A+ TEST BANK Katzung's Basic and Clinical Pharmacology, 16th Edition by Todd W. Vanderah, Chapters 1 – 66 A+

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TEST BANK Katzung's Basic and Clinical Pharmacology, 16th Edition by Todd W. Vanderah, Chapters 1 – 66 A+ ,,

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  • October 1, 2024
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TEST BANK Katzung's Basic and Clinical

Pharmacology, 16th Edition by Todd W. Vanderah,

Chapters 1 – 66 A+
Chapter 1: Introduction: The Nature of Drugs & Drug Development & Regulation



1. A nurse working in radiology administers iodine to a patient who is having a computed

tomography (CT) scan. The nurse working on the oncology unit administers chemotherapy to

patients who have cancer. At the Public Health Department, a nurse administers a measles-

mumps-rubella (MMR) vaccine to a 14-month-old child as a routine immunization. Which

branch of pharmacology best describes the actions of all three nurses?

A) Pharmacoeconomics

B) Pharmacotherapeutics

C) Pharmacodynamics

D) Pharmacokinetics

ANSWER: B

Feedback:

Pharmacology is the study of the biologic effects of chemicals. Nurses are involved with clinical

pharmacology or pharmacotherapeutics, which is a branch of pharmacology that deals with the

uses of drugs to treat, prevent, and diagnose disease. The radiology nurse is administering a drug

to help diagnose a disease. The oncology nurse is administering a drug to help treat a disease.

Pharmacoeconomics includes any costs involved in drug therapy.



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,Created By: A Solution


Pharmacodynamics involves how a drug affects the body and pharmacokinetics is how the body

acts on the body.



2. A physician has ordered intramuscular (IM) injections of morphine, a narcotic, every 4

hours as needed for pain in a motor vehicle accident victim. The nurse is aware this drug has a

high abuse potential. Under what category would morphine be classified?

A) Schedule I

B) Schedule II




C) Schedule III

D) Schedule IV

ANSWER: B

Feedback:

Narcotics with a high abuse potential are classified as Schedule II drugs because of severe

dependence liability. Schedule I drugs have high abuse potential and no accepted medical use.

Schedule III drugs have a lesser abuse potential than II and an accepted medical use. Schedule

IV drugs have low abuse potential and limited dependence liability.



3. When involved in phase III drug evaluation studies, what responsibilities would the nurse

have?

A) Working with animals who are given experimental drugs

B) Choosing appropriate patients to be involved in the drug study



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,Created By: A Solution


C) Monitoring and observing patients closely for adverse effects

D) Conducting research to determine effectiveness of the drug

ANSWER: C

Feedback:

Phase III studies involve use of a drug in a vast clinical population in which patients are asked to

record any symptoms they experience while taking the drugs. Nurses may be responsible for

helping collect and analyze the information to be shared with the Food and Drug Administration

(FDA) but would not conduct research independently because nurses do not prescribe

medications. Use of animals in drug testing is done in the preclinical trials. Select patients who

are involved in phase II studies to participate in studies where the participants have the disease

the drug is intended to treat. These patients are monitored closely for drug action and adverse

effects. Phase I studies involve healthy human volunteers who are usually paid for their

participation. Nurses may observe for adverse effects and toxicity.



4. What concept is considered when generic drugs are substituted for brand name drugs?

A) Bioavailability




B) Critical concentration

C) Distribution

D) Half-life

ANSWER: A

Feedback:



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, Created By: A Solution


Bioavailability is the portion of a dose of a drug that reaches the systemic circulation and is

available to act on body cells. Binders used in a generic drug may not be the same as those used

in the brand name drug. Therefore, the way the body breaks down and uses the drug may differ,

which may eliminate a generic drug substitution. Critical concentration is the amount of a drug

that is needed to cause a therapeutic effect and should not differ between generic and brand name

medications. Distribution is the phase of pharmacokinetics, which involves the movement of a

drug to the bodys tissues and is the same in generic and brand name drugs. A drugs half-life is

the time it takes for the amount of drug to decrease to half the peak level, which should not

change when substituting a generic medication.



5. A nurse is assessing the patients home medication use. After listening to the patient list

current medications, the nurse asks what priority question?

A) Do you take any generic medications?

B) Are any of these medications orphan drugs?

C) Are these medications safe to take during pregnancy?

D) Do you take any over-the-counter medications?

ANSWER: D

Feedback:

It is important for the nurse to specifically question use of over-the-counter medications because

patients may not consider them important. The patient is unlikely to know the meaning of orphan

drugs unless they too are health care providers. Safety during pregnancy, use of a generic

medication, or classification of orphan drugs are things the patient would be unable to answer but

could be found in reference books if the nurse wishes to research them.



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