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Tranexamic acid Questions and Answers
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Tranexamic acid Questions and Answers Another name for Tranexamic acid TXA Tranexamic acid class Synthetic antifibrinolytic Previous Play Next Rewind 10 seconds Move forward 10 seconds Unmute 0:00 / 0:15 Full screen Brainpower Read More Tranexamic acid mechanism of ac...

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  • September 30, 2024
  • 1
  • 2024/2025
  • Exam (elaborations)
  • Questions & answers

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  • tranexamic acid questions and answers
  • another name for tranexamic acid txa
  • tranexamic acid class synthetic antifibrinolytic

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Tranexamic acid Questions and Answers
Another name for Tranexamic acid - answer TXA

Tranexamic acid class - answer Synthetic antifibrinolytic

Tranexamic acid mechanism of action - answer Synthetic derivative of lysine that
binds to lysine binding site for fibrin on the plasminogen/plasmin molecule which
displaces plasminogen from the surface of fibrin and preserves/stabilizes the matrix
structure of fibrin and diminishes the ability of plasmin to lyse fibrin clots

Tranexamic acid indications - answer Hemorrhagic shock with hypotension (systolic
<90mmHg); blunt or penetrating trauma occurring within three (3) hours; bleeding
uncontrolled by direct pressure or tourniquet

Tranexamic acid contraindications - answer Hypersensitivity, DIC, renal failure,
isolated headinjuries, known DVT, hemorrhagic shock from non-traumatic events

Tranexamic acid adverse reactions - answer Headache, fatigue, abdominal
cramping, nausea, vomiting, joint and muscle pain

Tranexamic acid drug interactions - answer Effects of TXA will be decreased when
given with anticoagulants, bleeding prevention drugs and estrogen hormonal drugs

Tranexamic acid adult dose - answer 1g in 100mL NS IV/IO over 10 minutes loading
dose; follow with 1g over 8 hours

Tranexamic acid pediatric dose - answer Not recommended in children <15 y/o

Tranexamic acid duration of action-onset - answer unknown

Tranexamic acid duration of action-peak effect - answer unknown

Tranexamic acid duration of action-duration - answer 7-8 hours

Tranexamic acid special considerations - answer Do not use in traumatic cardiac
arrest or in patients with documented cervical cord injury and associated motor deficit

Tranexamic acid pregnancy category - answer B

How tranexamic acid is supplied - answer 1g/10mL (100mg/mL) vial

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