EXAMPLE: A dominant form of deafness: FF or Ff individuals can show mild, moderate or
profound deafness
Example of penetrance - answer✔Probability that a disease phenotype will appear when a
disease-related genotype is present. It is an all-or-none expression of a single gene.
Camptodactyly - answer✔Stiff, permanently bent little fingers (autosomal dominant)
Gene expression - answer✔.many factors can effect
. there are genotypes from which the phenotype is not easily predicted, because of gene-gene
interaction and gene-environment interaction
EXAMPLES: temperature and age
Genes - answer✔give consistent and regular patterns of expression
Pleiotropy - answer✔.The appearance of several apparently unrelated phenotypic effects caused
by a single gene.
.Refers to a Mendelian disorder with several symptoms
.Affected individuals express variable subsets of symptoms.
.Usually means that a gene is involved in multiple processes.
Pleiotropy example - answer✔Marfan's Syndrome .Has a high degree of variable expressivity
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