GMS 6504 MODULE 1-3 Exam 1 Questions
With 100% Verified Answers
What are System Independent Parameters? - answerAffinity
Efficacy
What are the parts of a system that are identified as System Dependent Parameters? -
answerNumber of receptors
Cellular machinery
Presence of other drugs
- Compe...
What is the Occupancy Theory? - answer✔Response is proportional to fraction of receptors that
are occupied
100% response is obtained when all receptors have ligand
What formula do we use to predict occupancy? - answer✔Langmuir equation
DR/Rt = r = D/D+Kd
How do we define response effect? - answer✔A+R --> (AR)
Intrinsic activity is depicted as what letter?
How is it defined? - answer✔Alpha
Multiplication factor describing ability of agonist to produce a stimulus
In terms of intrinsic activity, what is determined to be a full agonist? - answer✔α = 1
In terms of intrinsic activity, what is determined to me a partial agonist? - answer✔0 < α < 1
In terms of intrinsic activity, what is determined to be an antagonist? - answer✔α = 0
What is the formula for the estimation of relative efficacy? - answer✔R = f ( α x r x Rt )
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