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UVic Biol 467 Midterm I Exam Questions and Answers (Graded A)
UVic Biol 467 Midterm I Exam Questions and Answers
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UVic Biol 467 Midterm I Exam Questions
and Answers
Gastrulation ii- iiCorrect iiAnswers ii-blastula ii->gastrula iiwith iithe iiformation iiof iithree
iiembryonic iilayers
Dorsal iiblastopore iilip ii- iimesoderm iiinvolutes iiinto iithe iiembryo iito iiunderly iithe
iiectoderm iiin iithe iianimal iipole. iidisplaces iithe iiblastocoel iicavity
Vegetal iiPole ii- iiCorrect iiAnswers ii-Yolk, iiprovides iifood iisource, iidevelops iiinto iithe iigut
Ectoderm ii- iiCorrect iiAnswers ii-outermost iigerm iilayer; iiproduces iisense iiorgans,
iinerves, iiand iiouter iilayer iiof iiskin
Blastula/early iigastrula:
- iiDorsal iineural iiplate
- iiVentral iiepidermis
Mesoderm ii- iiCorrect iiAnswers ii-- iiDerived iifrom iitissue iithat iiinvoluted iiin iigastrulation
- iiBecomes iimuscle, iiblood
In iigastrula iiincludes: iinotochord, iimesenchyme, iiventral iimesoderm
Endoderm ii- iiCorrect iiAnswers ii-Becomes iithe iigut
Zebra iiFish ii- iiCorrect iiAnswers ii-- iiEasy iito iigenetically iimanipulate
- iiEasy iito iirear
- iiFast iigeneration iitime
- iiTransparent iiembryo's iiin iiearlier iistages ii(good iifor iifluorescence iimicroscopy)
Nematode: iiC. iielegans ii- iiCorrect iiAnswers ii-Simple iiorganization
Mice ii- iiCorrect iiAnswers ii-Closer iito iiour iineural iiorganization
Xenopus iiLaevis ii- iiCorrect iiAnswers ii-- iiEasy iito iicollect iieggs iiand iifertilize iithem
- iiSynchronous iidevelopment iiof iithousands iiof iiembryos
,Neural iiPlate iiStage ii- iiCorrect iiAnswers ii-- iiEnd iiof iigastrulation
- iiNeural iisystem iiis iia iiflat iisheet ii(neural iiplate iistage)
Epiboly ii- iiCorrect iiAnswers ii-General iiterm iifor iicells iiclosing iiover iian iiarea
Blastocoel ii- iiCorrect iiAnswers ii-Becomes iithe iibody iicavity
Neurulation ii- iiCorrect iiAnswers ii-- iiOccurs iiafter iigastrulation
- iiFormation iiof iithe iineural iitube
Notochord ii- iiCorrect iiAnswers ii-- iiMost iidorsal iimesoderm iistructure
- iiDoesn't iimake iiup iiany iispecific iistructure iiin iiadults
Archenteron ii- iiCorrect iiAnswers ii-The iiendoderm-lined iicavity, iiformed iiduring
iigastrulation, iithat iidevelops iiinto iithe iidigestive iitract iiof iian iianimal.
Neurula ii- iiCorrect iiAnswers ii-embryonic iistage iiwhen iithe iineural iitube iiis iiforming
When iiare iithe iicells iifated? ii- iiCorrect iiAnswers ii-When iithe iidorsal iilip iiis iiforming
Early iigastrula iistage: iiIf iiyou iitransplant iipresumptive iineural iiectoderm iiinto iian iiarea
iifated iito iibecome iiepidermis, iiit iiwill iibecome ii_______. ii- iiCorrect iiAnswers ii-Epidermis
iibecause iithe iidorsal iilip iihas iinot iiinvoluted iiyet
Late iigastrula iistage: iiIf iiyou iitransplant iipresumptive iineural iiectoderm iiinto iian iiarea
iifated iito iibecome iiepidermis, iiit iiwill iibecome ii________. ii- iiCorrect iiAnswers ii-neural
iiplate iitissue
The iidefault iistate iiof iiectoderm iiis ii______. ii- iiCorrect iiAnswers ii-Epidermis
When iiare iicells iidetermined? ii- iiCorrect iiAnswers ii-The iilate iigastrula iistage
Animal iiCap ii- iiCorrect iiAnswers ii-In iiamphibians, iithe iiroof iiof iithe iiblastocoel ii(in iithe
iianimal iihemisphere)
Default iistate iiis iiepidermis
Dorsal iilip iitransplantation iiexperiment ii- iiCorrect iiAnswers ii-Transplant iidorsal
iimesoderm iito iifuture iiventral iiside iiof iithe iiembryo ii(presumptive iiepidermis) iiin iia iihost
iiwhere iigastrulation iiis iijust iibeginning
What iidid iithe iiSpemann's iiorganizer iitransplant iiexperiment iishow? ii- iiCorrect iiAnswers
ii-- iiTransplanted iidorsal iilip iiinitiated iia iisecondary iisite iiof iiinvagination ii(secondary
iiaxis)
- iiDorsal iitissue iicould iiinitiate iigastrulation
, - iiMuch iiof iithe iineural iitube iiwas iimade iiof iihost iitissue ii(what iiwas iifated iito iibecome
iiepidermis). iiThis iishows iithe iitransplanted iimesoderm iiwas iiable iito iiinduce iineural
iitissue ii(beta-galactosidase iireporter iiin iidonor iitissue)
LiCl iigenerates iiembryos iithat iiare iicompletely ii_________ ii- iiCorrect iiAnswers ii-
dorsalized ii(lots iiof iineural iitissue ii& iidorsal iiendoderm)
What iidid iithey iiuse iito iidiscover iinoggin iiin iidorsalized iiembryos? ii- iiCorrect iiAnswers ii-
subtractive iihybridization iito iiidentify iimRNAs iienriched iiin iidorsal iitissue
In iisitu iihybridization iilooks iiat ii______ ii- iiCorrect iiAnswers ii-mRNA
The iisteps iiin iiin iisitu iihybridization ii- iiCorrect iiAnswers ii-1. iiPreserve iithe iitissue ii& iilock
iiit iiin iiplace
2. iiSpecific iiprobe iicomplimentary iito iithe iimRNA iiof iiinterest ii(base iipairing)
3. iiIncubate iisample iiwith iiantibodies iithat iirecognize iithe iiDIG ii(antibody iihas iialkaline
iiphosphatase ii-> iimakes iiblue iiprecipitate iiin iipresence iiof iisubstrate)
Noggin ii- iiCorrect iiAnswers ii-- iiBMP iiinhibitor ii(prevents iiligand iibinding)
- iinot iiexpressed iiin iineural iiectoderm
BMP ii- iiCorrect iiAnswers ii-bone iimorphogenic iiprotein
- iiTGF iibeta iisuperfamily
TGF iiBeta iipathway ii- iiCorrect iiAnswers ii-1. iiTGF iibeta iisuperfamily iiligand
2. iidimer iireceptor
3. iismad iiactivation ii(phosphorylation iiof iismad ii2,3)
4. iismad iidimerization ii(with iismad ii4)
5. iiactivation/repression iiof iigene iiexpression
Noggin iiprevents iiBMPs iifrom iibinding iithe iireceptor
When iiyou iiadd iinoggin iito iian iianimal iicap iiin iiisolation iiit iibecomes iiwhat? ii- iiCorrect
iiAnswers ii-Neural iitissue
The iiorganizer ii- iiCorrect iiAnswers ii-- iisource iiof iiBMP iiinhibitors
- iiinduced iiby iiNieuwkoop iicentre ii(dorsal iiendoderm) iiduring iithe iiearly/mid-blastula
iistage ii(even iifertilization) ii[wnt-signalling, iibeta-catenin]
wnt iisignalling iipathway ii- iiCorrect iiAnswers ii-wnt iibinds iifrizzled ii-> iiactivates
iidisheveled ii-> iiinhibits iiGSK3 ii-> iiallowing iinuclear iilocalization iiof iibeta-catenin
GSK-3 iinormally iiinhibits iibeta-catenin
_____ iiand ii_____ iiare iifunctionally iiredundant iiin iibrain iidevelopment iiin iimice ii-
iiCorrect iiAnswers ii-noggin, iichordin