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What Csmls Mock Exam Questions And Answers With Verified Solutions Latest Updated 2024
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What Csmls Mock Exam Questions And Answers With Verified Solutions Latest Updated 2024
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What Csmls Mock Exam Questions AndAnswers With Verified Solutions Latest
Updated 2024
What is a CBC ? - ANSWER✔✔ Complete Blood Count, an evaluation of formed
elements of blood , RBCs , WBCs and platelets . EDTA whole blood maintains the
cell's shape and size. preventing blood from clotting by binding by calcium
What is required for blood film preparation? - ANSWER✔✔ The object is to
spread the cells in monolayer without distorting them . The blood film is important
in the investigation and the management of blood cell disease
What is unique about the thickness of blood film ? - ANSWER✔✔ If the Hb is
increased , the angle of the spreader should be decreased. If the Hb is decreased the
angle of the spreader should be increased
What are the features of a well made blood film ? - ANSWER✔✔ Correct size
drop of blood
Film is 2/3 of the length of the slide
Film is finger shaped with a slightly rounded feathered edge
Angle of the spreader should be 35 degrees
Film is smooth with no holes or streaks
What are the steps required when staining and fixing a blood film ? -
ANSWER✔✔ Allow blood film to dry completely before staining. Do not blow
dry as moisture from breath will cause RBC artifact. Methanol is thge fixative of
choice , stain has methanol. Timing and pH are critical
,What are coagulation tests? - ANSWER✔✔ Plasma is required. Citrate is the
anticoagulant of PT + PTT. Sodium citrate binds to calcium preventing
coagulation. Tubes must be drawn full capacity
What is Hemoglobinopathy? - ANSWER✔✔ Abnormal chain of Hb
What is Thalassemia ? - ANSWER✔✔ Failure to produce alpha or beta chains
What is the Hb Normal value for Infants ? - ANSWER✔✔ 160 - 230 g/L
What is the Hb Normal value for a Toddler ? - ANSWER✔✔ > 100 g/L
What is the Hb Normal value for a male? - ANSWER✔✔ 140-180 g/ L
What is the Hb Normal value for a female ? - ANSWER✔✔ 120- 160 g/L
What are the critical Hb values ? - ANSWER✔✔ Low < 60 g/L , causes bleeding /
heart failure
High > 200 g/L polycythemia, severe burns, chronic obstructive pulmonary disease
and CHF
What is Hematocrit? - ANSWER✔✔ Also called PCV. Micro Hct is the volume of
RBCs after centrifuging whole blood for 5 minutes @ 12, 000 rpm. Comprises
RBCs that are normally 40 - 50 % of blood volume. Requires a small volume of
blood. Lavender top tube, venous blood or capillary blood collected directly into
heparinized capillary tubes. SHould be centrifuged within 4 hours of collection
,What is the Hct Normal value for an infant? - ANSWER✔✔ 0.50 - 0.60
What is the Hct Normal value for a toddler? - ANSWER✔✔ 0.35 -0.42
What is the Hct Normal value for a male ? - ANSWER✔✔ 0.40-0.50
What is the Hct normal value for a female? - ANSWER✔✔ 0.35-0.50
What is the Hct Critical Values? - ANSWER✔✔ < 0.20 and > 0.60
What are some of the sources of error for Hct? - ANSWER✔✔ Improper sealing of
capillary tube (D) due to loss of RBCs
Increase concentration of anticoagulant (D) due to unfilled tube
Improper mixing of blood (I) or (D)
Time & speed of centrifuge (I) due to trapped plasma
Improper collection of specimen (I) or (D)
Delay in reading (I) due to packing of RBC
Buffy coat included (I)
What is the structure of a WBC? - ANSWER✔✔ Approx 10 - 20 um in diameter
(2-3 size of RBC) , can count under 400 X magnification (high dry) can see detail
under 1000 X magnification (oil immersion) , cells are nucleated , flexible
membrane variable shape, resists lysis types: granulocytes, lymphoctyes,
monocytes
, What is required for the manual WBC Principle Count ? - ANSWER✔✔ Dilute
blood with fluid that lyses RBCs and stains WBCs, counts the WBCs in a known
volume of blood, calculate cells / L
What is the normal value of WBC in an adult? - ANSWER✔✔ 4.5 -11.0 x10 9/L
What is the normal value of WBC in an infant ? - ANSWER✔✔ 9.0 - 30.0 x 10 9/
L
What is the critical value for WBC? - ANSWER✔✔ < 1x10 9 /L and > 50 x 10 9 /
L
What is the RBC Principle Count? - ANSWER✔✔ Dilute well mixed EDTA blood
with isotonic fluid, count RBCs in an known volume of blood. Calculate cells/ L
What is the RBC normal value for a male? - ANSWER✔✔ 4.5 - 6.0 x 10 12 / L
What is the normal RBC value for a female? - ANSWER✔✔ 4.0 - 5.5 x 10 12/L
What is ESR ? - ANSWER✔✔ Rate at which RBCs fall within a set time.
Rouleaux, fibrinogen and globulin increase ESR, high RBC some RBC shapes will
decrease ESR
What is the Manual Westergreen Method? - ANSWER✔✔ 200 nm open ended
tube specimen sample EDTA blood diluted 4:1 with citrate black tube. Use pipette
filler to fill ESR tube until cotton is wet to prevent leaking. Set up vertically in
rack, record mm of RBCs that fell in an hour
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