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Nurs 125 Exam Questions And Correct Answers
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Nurs 125 Exam Questions And Correct AnswersPharmacology
study of drugs
Pharmacotherapeutics clinical pharmacology
use of drugs in the prevention and treatment of disease, effects of, how the body
responds, concerns
Preclinical
Not in humans. In vitro/in vivo
purpose of preclinical trials
To find out if they have the effect on living tissue
To assess for adverse effects
Identify reactions
Phase I
Human volunteers, investigation of the effect in humans adverse effects and toxicity.
70% continue to next phase. May find a therapeutic side effect
Phase II
Patients with dz, 33% continue. Reasons for discard include not making enough $ or not
better than current drugs
Phase III
Lager population sample. 25-30% continue to FDA approval. Discarded for unexpected
responses and unacceptable side effects
FDA approval
Drug evaluated by FDA; if approved, may be marketed
How long does FDA approval take
5-6 years
Fast tracked
, For deadly dz with no other available treatment
Breakthrough status
Clinical evidence that there's ability to treat serious diseases with substantial
improvement over current treatment or in the absence of another drug
Brand name
Pharmaceutical company given name
Generic name
the original designation that a drug is given when the drug company that developed it
applies for the approval process
Chemical name
chemical structure of the drug
Phase IV Clinical Trial
Post-marketing, continue assessing therapeutic value and monitor less common
adverse events
What does the FDA label include
Approved uses, risks/benefits, absorption, distribution, metabolism, excretion
Off label
May lead to approval for new use. Common for geriatric and peds use
NSAIK
NSAIDS
N = Naproxen
S = Salicylate acid (aspirin)
A = acetylsaliclyic acid (aspirin)
I = Ibuprofen / Indomethacin
K = Ketorolac (toradol)
Most commonly used NSAID
Naproxen
NSAIDs are given for
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