NAPLEX 2021: HIV Exam Questions With Verified/Correct Answers
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Course
NAPLEX HIV
Institution
NAPLEX HIV
HIV is an ____ retrovirus that uses machinery in ______ cells to replicate - ANSWER-RNA retrevirus; uses CD4+ T helper cells
AIDS is diagnosed when: __________ or _________ - ANSWER-CD4 count <200 OR presence of an AIDS-defining condition (i.e. opportunistic infections or Kaposi's sarcoma)
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NAPLEX 2021: HIV Exam Questions With
Verified/Correct Answers
HIV is an ____ retrovirus that uses machinery in ______ cells to replicate - ANSWER-
RNA retrevirus; uses CD4+ T helper cells
AIDS is diagnosed when: __________ or _________ - ANSWER-CD4 count <200 OR
presence of an AIDS-defining condition (i.e. opportunistic infections or Kaposi's
sarcoma)
HIV can be transmitted through (5) - ANSWER-blood, semen, vaginal secretions, anal
secretions, breast milk
CDC recommends HIV screening for ________ (who and how often). - ANSWER-
everyone aged 13-64 at least once
High risk: annually
Who is considered high risk for HIV (4) - ANSWER-IV drug users
High risk sexual activity
Hx of STI
Hx of hepatitis or TB
When is the HIV viral load high enough to test? - ANSWER-2 weeks post-infection for
antigens
4-6 weeks for antibodies
Initial screening for HIV is done with what test and what does it test for? - ANSWER-
H1H2AA screening test (HIV1/HIV2 antigen/antibody)
Tests for HIV p24 antigens and HIV2/HIV2 antibodies
If the initial test is positive for HIV, what is the next step? - ANSWER-Confirm positive
test with H1H2ADI (HIV1/HIV2 antibody differentiation immunoassay)
Differentiates between HIV1 (most common in US) and HIV2)
First test for HIV positive, then second test done:
Results negative-->
Results positive--> - ANSWER-Results negative--> Nucleic acid test (NAT)
Results positive--> Diagnosis and subtype confirmed
, OTC HIV test:
Name:
What it tests:
When can you use it: - ANSWER-OraQuick --> Detects HIV Ab
Maraviroc works on stage ___ of HIV replication - ANSWER-Stage 1:
Binding/Attachment
Trogarzo works on stage ___ of HIV replication - ANSWER-Stage 1:
Binding/Attachment
Fuzeon works on stage ___ of HIV replication - ANSWER-Stage 2: Fusion
NNRTIs/NRTIs work on stage ___ of HIV replication - ANSWER-Stage 3: Reverse
transcription
INSTIs work on stage ___ of HIV replication - ANSWER-Stage 4: Integration
PIs work on stage ___ of HIV replication - ANSWER-Stage 7: Budding and Maturation
Normal CD4+ cell count - ANSWER-800-1200
CD4 count is a marker of _______
HIV viral load is a marker of _______ - ANSWER-CD4-->immune function
viral load --> response to ART
ART treatment goal - ANSWER-undetectable viral load
What should be tested before initiation of ART (6) - ANSWER-CD4
HIV viral load
Hep B/C
Pregnancy
HLA-B*5701 allele (if considering abacavir)
Tropism assay (is considering maraviroc)
Acceptable adherence to prevent HIV resistance: - ANSWER-95% adherence
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