ABIM REVIEW - KNOWMEDGE+FIRST AID HIGH YIELD+ABIM
ROTE MEMORIZATION
What vitamin deficiency can occur with use of Isoniazid (INH)? - Answers -Vitamin B6
(Pyridoxine)
What is the fundoscopic exam finding often seen with idiopathic intracranial
hypertension (Pseudotumor cerebri)? - Answers -Papilledema
What is the ideal LDL goal in CAD patients or CAD equvialent patients? - Answers -
Less than 70 mg/dl
What is the inheritance pattern for Hereditary Hemorrhagic Telangiectasia (HHT)? -
Answers -Autosomal dominant. HHT is also known as Osler-Weber-Randau syndrome
What is the most common symptom of Hereditary Hemorrhagic Telangiectasia (HHT)? -
Answers -Epistaxis (nose bleeding)
What are the possible agents for treating hypertension in pregnant women? - Answers -
Hydralazine, Labetalol, Alpha methyldopa
What is the laboratory screening test for chronic alcohol abuse? - Answers -
Carbohydrate free transferrin level elevated
What blood test is the initial screening test for suspected systemic mastocytosis? -
Answers -Serum tryptase level
Strong family history of premature heart disease + patient has a low HDL. What level is
likely to be elevated? - Answers -Lipoprotein a or Lp(a)
What vitamin or mineral deficiency is associated with rash and alopecia in patients on
TPN feeding? - Answers -Zinc deficiency
What is the goal uric acid level to prevent further attacks in patients with gout? -
Answers -Less than 6mg/dl
What class of medication is the first-line treatment of renal crisis in scleroderma? -
Answers -ACE inhibitors
What is the most specific test for diagnosing rheumatoid arthritis? - Answers -Anti-
citrullinated protein (anti-CCP) antibody
What are the two most common nerve root impingements in lower back pain? - Answers
-L5 and S1
,Which agent used in the treatment of rheumatoid arthritis requires frequent eye exams?
- Answers -Hydroxychloroquine
Which antibody is associated with CREST syndrome? - Answers -Anti-centromere
What is the most common cause of septic arthritis in inviduals greater than 40 years of
age? - Answers -Staph aureus
What is the most sensitive method of diagnosing avascular necrosis? - Answers -MRI
What HLA marker can often be associated with ankylosing spondylitis? - Answers -HLA-
B27
With systemic lupus erythematosus exacerbation, what would you expect the
complement (high/low), anti-dsDNA (pos/neg) and ESR (high/low) levels to be? -
Answers -Low complement, pos anti-dsDNA, high ESR
Patient with rheumatoid arthritis on leflunomide decides she wants to get pregnant.
What is the best next step in management? - Answers -Give cholestyramine for 9-11
days
Before starting patient on TNF-alpha inhibitors, what test should be performed? -
Answers -Purified protein derivative (PPD) tuberculin skin test
If pts with osteoarthritis present with morning stiffness, what length of time should it not
exceed? - Answers -30 minutes
Greater than what value is the white blood cell (WBC) count expected to be in cases of
septic arthritis? - Answers -More than 50,000/uL
Of the MCP, PIP, and DIP joint, which of the following is least likely to be involved with
rhematoid arthritis? - Answers -DIP joint
With osteoarthritis, what would you expect the ESR and CRP levels to be? - Answers -
Normal (versus elevated in rheumatoid arthritis)
Which knee test can indicate that patient has a lateral collateral ligament tear? -
Answers -Positive varus test
What is the most common extra-articular manifestation of rheumatoid arthritis? -
Answers -Rheumatoid nodules
What rheumatological condition can often be associated with temporal arteritis? -
Answers -Polymyalgia rheumatica (PMR)
,Patient with polymyositis is on high dose steroids. CPK levels are improving but
weakness worsening. What to do? - Answers -Taper down on the steroids
Back pain that improves with leaning forward is the the classic presentation of what
musculoskeletal condition? - Answers -Spinal stenosis
Patient who uses cocaine and has a weak handshake. What is the likely diagnosis? -
Answers -Inclusion body myositis
What is the leading cause of death in patients with systemic lupus erythematosus? -
Answers -Cardiovascular disease
What is the initial diagnostic test to check in an individual you suspect to have temporal
arteritis? - Answers -Erythrocyte sedimentation rate (ESR)
What is the initial diagnostic test to check in an individual you suspect of having
polymyositis? - Answers -Creatine phosphokinase (CPK) or Creatinine kinase (CK)
Loss of passive flexion of the foot when the calf is squeezed with achilles tendon tears
is known as what test? - Answers -Positive Thompson test
What is the syndrome that contains the triad of ptosis, miosis, and anhidrosis? -
Answers -Horner's Syndrome
Which vitamin toxicity may lead to idiopathic intracranial hypertension (Pseudotumor
cerebri)? - Answers -Vitamin A
What enteropathic organism is most often associated with Guillain-Barre Syndrome -
Answers -Campylobacter jejuni
Optic chiasm compression will lead to what eye abnormality? - Answers -Bitemporal
hemianopsia
What are the reflexes you would expect in an individual who has antibodies to post
synaptic acetylcholine receptors? - Answers -Normal
Which class of antibiotics is most notoriously contraindicated in individuals with
myasthenia gravis? - Answers -Aminoglycosides
An obese individual with headaches is found to have a high opening pressure during
lumbar pressure. What is the best medication for this pt's likely condition? - Answers -
Acetazolamide (Carbonic anhydrase inhibitor)
What reflexes (increased/decreased) would you expect with someone who is diagnosed
with West Nile Virus meningits? - Answers -Decreased
, What is the triad of symptoms you would expect in a patient with normal pressure
hydrocephalus (NPH)? - Answers -Ataxia (wide based gait), dementia, and urinary
incontinence
What are the MRI T1 (increased/decreased) and T2 (increased/decreased) signal
changes seen in patients with multiple sclerosis? - Answers -Decreased T1 and
Increased T2
In patient with antibodies to pre-synaptic acetylcholine receptors, are reflexes increased
or decreased? - Answers -Decreased (condition is Eaton-Lambert Syndrome)
Which class of medication is used to prevent vasospasm in patients with subarachnoid
hemorrhage? - Answers -Calcium channel blockers (eg. nimodipine, nifedipine)
Blood pressure greater than or equal to what value is a contraindication for t-PA therapy
in patients with ischemic stroke? - Answers -Systolic blood pressure greater than
185mmHg or Diastolic blood pressure greater than 110mmHg
What area of the brain is affected with the diagnosis featuring bradykinesia, cogwheel
rigidity, postural instability and resting tremor? - Answers -Substantia nigra (likely
diagnosis is Parkinson's disease)
Patient is found to have left homonymous quadrantanopia. Where is the lesion? -
Answers -Right optic radiation
Bilateral lateral rectus palsy is often seen with what vascular condition? - Answers -
Cavernous sinus thrombosis
Finasteride, used to assist patients with benign prostatic hyperplasia , acts on which
enzyme to inhibit conversion of testosterone to dihydrotestosterone? - Answers -5 alpha
reductase
Muddy brown casts in a urinalysis is a clue towards which renal process? - Answers -
Acute tubular necrosis (ATN)
Which form of nephrotic syndrome is most associated with heroin use? - Answers -
Focal segmental glomerulosclerosis
What type of kidney stones are often implicated in recurrent UTIs? - Answers -Struvite
(Magnesium ammonium phosphate) stones
What are the organisms that may lead to struvite stones? - Answers -Urea-splitting
bacteria (Proteus, Klebsiella, or Pseudomonas)
What is the gold standard imaging modality for diagnosing kidney stones? - Answers -
Noncontrast spiral CT
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