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BCTXP Exam: Lung Transplantation Questions with correct answers

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Indications for lung txp Correct Answer-Group A: obstructive lung disease -COPD, emphysema, bronchiectasis Group B: pulmonary vascular disease -Pulmonary HTN Group C: CF of immunodeficiency disorders -CF, common variable immune deficiency Group D: restrictive lung disease -Idiopathic pulmona...

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  • September 26, 2024
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BCTXP Exam: Lung Transplantation Questions with
correct answers
Indications for lung txp Correct Answer-Group A: obstructive lung
disease
-COPD, emphysema, bronchiectasis
Group B: pulmonary vascular disease
-Pulmonary HTN
Group C: CF of immunodeficiency disorders
-CF, common variable immune deficiency
Group D: restrictive lung disease
-Idiopathic pulmonary fibrosis, re-txp


Most common lung txp indications by diagnosis group Correct Answer-
D
A
C
B


Which of the following is the leading indication for lung transplant in
the United States?
a) Chronic obstructive pulmonary disease
b) Cystic fibrosis
c) Pulmonary fibrosis

,d) Pulmonary arterial hypertension Correct Answer-C (used to be
COPD)


Lung txp listing criteria Correct Answer-Chronic, end-stage lung disease
with:
• >50% risk of death from lung disease within 2 years without lung
transplant
• >80% likelihood of surviving at least 90 days after lung transplant
• >80% likelihood of surviving 5 years from a general medical
perspective


Lung txp absolute CI Correct Answer-• Malignancy in the last 5 years (2
years low risk)
• Untreatable significant dysfunction of another major organ system
(unless multiorgan tx)
• Uncorrected atherosclerotic disease with end‐organ ischemia or CAD
not amenable to revascularization
• Acute medical instability (e.g. acute sepsis, myocardial infarction, liver
failure)
• Uncorrectable bleeding diathesis
• Chronic infection with highly virulent and/or resistant microbes that
are poorly controlled
• Active Mycobacterium tuberculosis infection
• Significant chest wall or spinal deformity
• BMI > 35 kg/m2
• Current or history of repeated or prolonged nonadherence

, • Psychiatric or psychologic condition associated with the inability to
cooperate with the medical team and/or adhere with complex therapy
• Absence of an adequate or reliable social support system
• Severely limited functional status with poor rehabilitation potential
• Substance abuse or dependence


Lung txp relative CI Correct Answer-• Age > 65 years with low
physiologic reserve; Age > 75 years are unlikely to be candidates **age
by itself should not be considered a contraindication
• BMI 30‐34.9 kg/m 2, especially if truncal obesity
• Progressive or severe malnutrition
• Severe, symptomatic osteoporosis
• Extensive prior chest surgery with lung resection
• Mechanical ventilation and/or ECLS **carefully selected candidates
without other organ dysfunction may be transplanted
• Colonization or infection with highly resistant or highly virulent
bacteria, fungi, and certain strains of Mycobacteria
• Infection with Burkholderia or multi‐drug‐ resistant Mycobacteria
abscessus
• If HBV or HCV, absence of cirrhosis/portal HTN stable on appropriate
therapy
• If HIV, undetectable HIV RNA on stable ART
• Atherosclerotic disease burden sufficient to put the patient at risk for
end‐organ disease
• Other medical conditions should be optimally treated before
transplantation

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