NURS8024 Pharm Exam 3 (antimicrobial part 1)-
Questions and Answers
Minimum inhibitory concentration (MIC) Correct Ans-Estimate of the drug sensitivity of a
pathogen for comparison with anticipated levels in blood or tissues
Lowest concentration of antibiotic inhibiting bacterial growth
Effective antimicrobial Tx should have antibiotic concentration> MIC
Post-antibiotic effect (PAE) Correct Ans-Antibacterial effect that persists after drug
concentration falls below the minimum inhibitory concentration (MIC)
Susceptibility testing Correct Ans-Culture indicates the sensitivity of the isolated pathogen
to specific antimicrobial drugs
Predicts MIC
- estimate of the drug sensitivity of pathogen compared to the anticipated levels in the blood
or tissues
, NURS8024 Pharm Exam 3 (antimicrobial part 1)-
Questions and Answers
Common gram negative aerobes Correct Ans-Moraxella catarrhalis
neisseria gonorrhoeae
Haemophilius influenzae (HIB)
Space bugs Correct Ans-Hard to treat organisms
Serratia
Pseeudomonas aeriginosa
Acinetobacter helocobacter
Citrobacter
Enterobacter
Anaerobes Correct Ans-Thrive w/out oxygen
Virulence factors
Release exotoxins
Local microbiota enter previously sterile tissue
common anerobes Correct Ans-Clostridium perringes, difficile (C-diff)
Fusobacterium
Actinomyces (abdominal infections), bacteroides fragilis- anarobe most commonly isolated
from intraabdominal infections and bacteremia
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