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NURS 660: PSYCHOPHARM (Exam 1) QUESTIONS WITH COMPLETE SOLUTIONS $7.79   Add to cart

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NURS 660: PSYCHOPHARM (Exam 1) QUESTIONS WITH COMPLETE SOLUTIONS

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NURS 660: PSYCHOPHARM (Exam 1) QUESTIONS WITH COMPLETE SOLUTIONS .- 5-HT2A antagonist Function: - ANSWER-o Blocks 5-HT2A receptors causing a Decrease in extrapyramidal symptoms. .- D1 o low binding affinity - ANSWER-o Augmenting D1 Receptor agonist TX of parkinsons .-ONES These drugs ...

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  • September 25, 2024
  • 34
  • 2024/2025
  • Exam (elaborations)
  • Questions & answers
  • NURS 660
  • NURS 660
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NURS 660: PSYCHOPHARM (Exam 1) QUESTIONS WITH
COMPLETE SOLUTIONS

.- 5-HT2A antagonist Function: - ANSWER-o Blocks 5-HT2A receptors causing a Decrease in
extrapyramidal symptoms.



.- D1

o low binding affinity - ANSWER-o Augmenting D1 Receptor agonist TX of parkinsons



.-ONES



These drugs - ANSWER-Prolong QTC



.2D6 inHibitors: (4) - ANSWER-► Fluoxetine (Prozac)

► Paroxetine (Paxil)

► Bupropion (Wellbutrin)

► Duloxetine (Cymbalta)



.2D6 substrates - ANSWER-



.2nd generation works by - ANSWER-Blocking receptors D2 and 5-HT2A



.5 antipsychotics with minimal antichoinergic properties. - ANSWER-Haldol

Ariprazole

Quitapine

Risperidone

Ziprasidone



.5-HT "TWITCHY FROG" Serotonin Syndrome - ANSWER--Agitated

,-Sweating

-Fever

-Hyperreflexia

-Dilated pupils



.5-HT 1A receptor - ANSWER-Think anxiety and depression



o Partial agonist: Example: busbar



.5-HT2a antagonists examples (3) - ANSWER-Clozapine

Riseridone

Olanzapine



.5-HT2C Receptor:



o SIDE EFFECT: - ANSWER-Weight gain



.5-HT2C Receptor:

- May contribute to ___ ___ and ____effects - ANSWER-Improved cognition and antidepression effects



.5-HT6 Receptor: how does it work? - ANSWER-No one knows



.5HT2A Receptor reduces - ANSWER-extrapyramidal side effects caused by D2's blockade



.Abilify is a substrate of____ and _____ - ANSWER-2D6 and 3A4



.Acute dystonia: 2 types - ANSWER-Toricollic and oculogyric crisis



.Adverse effects of haldol - ANSWER-dystonia, TD

,.Affective symptoms of schizophrenia - ANSWER-dysphoria, suicidality, hopelessness



.Agonism at D2 causes - ANSWER-Motor SE, Akathisia

Nausea

Vomiting



.anticholinergic (antimuscarinic) blocks - ANSWER-acetylcholine at muscarinic receptors.



.anticholinergic = - ANSWER-antimuscarinic



.Anticholinergic general effects: - ANSWER-- Tachycardia

- Dry as a bone

- Mad as a hatter (confusion)

- Blind as a bat



.Anticholinergic side effects (5) - ANSWER-Dry mouth Tachycardia

Urinary retention Blurred vision Constipation



.Aripiprazole acts as a(n) ______________ in the mesolimbic system and as a(n) ____________ in the
prefrontal cortex. - ANSWER-antagonist, agonist

D2 partial agonist



.Ariprazole has lower _____, ______, and ____ _____ side effects - ANSWER-EPS

QTc

Weight gain



.Ariprazole is associated with new onset _______ _________ due to increased dopamine activity. -
ANSWER-impulse control

, .Avoid

__________________ when prescribing clozapine. - ANSWER-anticholinergics



.Axons sent via the mesocortical pathway mediate _________ symptoms in the DLPFC and _______
symptoms in the VMPFC - ANSWER-cognitive symptoms and affective



.BAD drug combos: Clozapine + Carbamazepine (tegretol) - ANSWER-Supresses bone marrow

Decrease clozapine levels



.BAD drug combos: Lurasidone (Latuda) + Carbamazepine (tegretol) - ANSWER-Tegretol kills Latuda



.BAD drug combos: Quiteipine + Carbamazepine (tegretol) - ANSWER-Decreased seroquel level, if CBZ is
stopped reversal induction occurs



.BEN neutropenia - ANSWER-500-999 μL



.BEN patients: Normal ANC range for Clozaril - ANSWER-≥1,000 μL



.Blocking 5-HT2A receptors increases release of _______ in basal ganglia, this prevents development of
______ _____ _______ which leads to Tardive Dyskinisia - ANSWER-dopamine



D2 receptor hypersensitivity



.Blocking Alpha 1 adrenergic causes (3) - ANSWER-Orthostatic hypotension, cardiac problems, sexual
dysfunction



.Blocking histamine causes: - ANSWER-Sedation, weight gain



.Blocking Muscarinic receptors causes (5) - ANSWER-Anticholinergic side effects:

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