- May contribute to ___ ___ and ____effects - ANSWER-Improved cognition and antidepression effects
.5-HT6 Receptor: how does it work? - ANSWER-No one knows
.5HT2A Receptor reduces - ANSWER-extrapyramidal side effects caused by D2's blockade
.Abilify is a substrate of____ and _____ - ANSWER-2D6 and 3A4
.Acute dystonia: 2 types - ANSWER-Toricollic and oculogyric crisis
.Adverse effects of haldol - ANSWER-dystonia, TD
,.Affective symptoms of schizophrenia - ANSWER-dysphoria, suicidality, hopelessness
.Agonism at D2 causes - ANSWER-Motor SE, Akathisia
Nausea
Vomiting
.anticholinergic (antimuscarinic) blocks - ANSWER-acetylcholine at muscarinic receptors.
.anticholinergic = - ANSWER-antimuscarinic
.Anticholinergic general effects: - ANSWER-- Tachycardia
- Dry as a bone
- Mad as a hatter (confusion)
- Blind as a bat
.Anticholinergic side effects (5) - ANSWER-Dry mouth Tachycardia
Urinary retention Blurred vision Constipation
.Aripiprazole acts as a(n) ______________ in the mesolimbic system and as a(n) ____________ in the
prefrontal cortex. - ANSWER-antagonist, agonist
D2 partial agonist
.Ariprazole has lower _____, ______, and ____ _____ side effects - ANSWER-EPS
QTc
Weight gain
.Ariprazole is associated with new onset _______ _________ due to increased dopamine activity. -
ANSWER-impulse control
, .Avoid
__________________ when prescribing clozapine. - ANSWER-anticholinergics
.Axons sent via the mesocortical pathway mediate _________ symptoms in the DLPFC and _______
symptoms in the VMPFC - ANSWER-cognitive symptoms and affective
.BAD drug combos: Clozapine + Carbamazepine (tegretol) - ANSWER-Supresses bone marrow
.BAD drug combos: Quiteipine + Carbamazepine (tegretol) - ANSWER-Decreased seroquel level, if CBZ is
stopped reversal induction occurs
.BEN neutropenia - ANSWER-500-999 μL
.BEN patients: Normal ANC range for Clozaril - ANSWER-≥1,000 μL
.Blocking 5-HT2A receptors increases release of _______ in basal ganglia, this prevents development of
______ _____ _______ which leads to Tardive Dyskinisia - ANSWER-dopamine
.Blocking histamine causes: - ANSWER-Sedation, weight gain
.Blocking Muscarinic receptors causes (5) - ANSWER-Anticholinergic side effects:
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