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NSG 533 Advanced Pathophysiology Exam 4 Questions With All Correct Answers 2024/2025
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NSG 533 Advanced Pathophysiology Exam 4 Questions With All Correct Answers 2024/2025
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NSG 533 Advanced PathophysiologyExam 4
Hemoglobin A2 (HbA2)
The minor person shape of hemoglobin, happens in about 2-3% of individuals. Contains 2 alpha
and a pair of delta globin chains.
Hemoglobin F (HbF)
The predominant fetal form of hemoglobin with a greater affinity to oxygen than HgA. Will be
absolutely replaced via 6 months of existence. Contains 2 alpha and a pair of gamma globin
chains.
Hemoglobin S (HbS)
Form of hemoglobin with a dysfunctional beta chain ensuing in Sickle trait or disorder.
Normal price for RBCs
four.Five-6 million cells/uL of blood
Definition and everyday price for Hgb
A dimension of the mass of hemoglobin; > 13 g/dL in guys, > 12 g/dL in girls
Definition and normal fee for Hct
A degree of the % of whole blood with intact RBC; 40-50% in men, 35-45% in women
What is the relation of hematocrit to hemoglobin?
3x
Definition and ordinary price of imply corpuscular extent (MCV)
A measure of the common extent of a RBC; eighty-100 fl.
, What is a normal reticulocyte remember, and what is the which means of a excessive or low
value?
Normal: 0.5-2%. Low = underproduction, high = hemolysis or active bleeding
Total iron binding capacity (TIBC)
Measures the blood's ability to bind iron to transferrin. In iron deficiency anemia, iron stage
could be low however TIBC can be high. Normal = 240-450 mcg/dL
Haptoglobin
An acute segment reactant protein made via the liver that preserves iron by way of irreversibly
binding loose hemoglobin from lysed RBCs.
Microcytic anemia
An underproduction anemia characterized by using abnormally small erythrocytes that
incorporate strangely decreased amounts of hemoglobin. Typically iron deficiency. MCV < 80 fl.
State lab findings visible in iron defiency anemia
MCV < 80 fl., reticulocyte depend < zero.Five%, ferritin < a hundred ng/mL, excessive TIBC, low
serum iron < 30, bone marrow biopsy showing absense of iron stores
What is the gold standard diagnostic test for iron deficiency anemia?
Bone marrow biopsy; not usually necessary
What are possible etiologies of iron deficiency anemia?
Blood loss (GI or menstrual), inadequate intake of meats, malabsorption (gastrectomy, bariatric
surgery, celiac dx, IBS)
Macrocytic anemia
An underproduction anemia that arises commonly from abnormalities that hinder the maturation
of erythroid precursors in the bone marrow. Typically B12 or folate deficiency. MCV > one
hundred fl.
True or fake: folate deficiency is the most common cause of macrocytic anemia.
True; the body handiest shops a four-five month deliver of folate.
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