Definition 1 of 470
What happens once the antigen-antibody complex is formed in Type III hypersensitivities?
The complex causes the body to produce more antibodies
Once the complex is formed, they are deposited in vessel walls or extravascular tissue
and trigger an immune and inflammatory response
The complex enhances the immune response without inflammation
The complex is immediately eliminated by the body
Definition 2 of 470
treatment for PCP pneumocystis Jiroveci pneumonia
Sarco-
Bactrim
AB positive
Edema
Definition 3 of 470
coagulative, liquefactive, caseous, fat, gangrenous
etiology of edema
interstitial pattern of fluid shift
metabolic acidosis
5 Types of Necrosis
,Definition 4 of 470
pH >7.45
Paco2 normal
Bicarb >26
T:
Ck enzymes
Kinin system Activated
Metabolic alk
Uncompensated
Definition 5 of 470
What does alloimmunity imply?
Describes a benign reaction to environmental factors
Indicates the body's failure to produce any antibodies
Refers to the immune system attacking its own cells
Implies the formation of antibodies to foreign antigens (exogenous antigens)
Definition 6 of 470
E-byproduct of purine degradation
CI-accumulation gets deposited into the tissues of the kidney, heart, earlobes, joints
-liver can produce more uric acid than can be eliminated
-diuretics can trigger kidneys to increase absorption of uric acid
-over accumulation or under secretion of uric acid can result in gout
Urate accumulation Effects and Clinical Implications
Metastatic Calcification Effects and Clinical Implications
Acid Base Balance effect on K+
Hepatocellular damage:Alcoholic Hepatitis
,Definition 7 of 470
from GI losses or diuretics
C.M. Volume depletion, orthostatic hypotension, tachycardia, lack of organ perfusion
hypermagnesemia
hyperkalemia
hypovolemic hypernatremia
Hypovolemic Hypernatremia etilolgy
Definition 8 of 470
seizures, coma, areflexia, incontinence, death
Tumor Marker:Beta Human Chorionic gonadotropin
Tumor Marker:Alpha Fetoprotein
AB
Serum Na level: < 120mEq/L clinical manifestations
Definition 9 of 470
E. increased acid production, loss of bicarb, diminished renal excretion of hydrogen
C.M hyperventilation (compensatory), h/a, n/v/d, dehydration, hypotension
pH <7.4 HCO3 <22
metabolic acidosis
Dystrophic Calcification
Oncotic pressure
Hypercalcemia
, Definition 10 of 470
hydrostatic pressure promotes the movement of about 10% of fluid along with small amount of
protein into lymphatics which eventually returns to the circulation
Clinical manifestations of fluid volume deficit
Growth factors
Interstitial pattern of fluid shift
Fluid volume deficit pathophysiology
Definition 11 of 470
Type III chronic, multi-system, inflammatory disease, Primarily in women 20-40
Antibodies formed against DNA and nucleus
Butterfly rash, photosensitivity
Systemic Lupus Erythematosus
Coagulation cascade activated
Type III Hypersensitivity
Euvolemic Hypernatremia
Definition 12 of 470
What does IgE do upon initial exposure to the allergen?
Igg and c3b may also bind to the antigen and the macrophages and trigger cell lysis
through phagocytosis
It is a t-cell mediated reaction that occurs 11-14 days after first exposure and 5-6 days
after the second exposure. this results in mononuclear infiltration, decreased circulation
and tissue necrosis.
It binds with the allergen
It primes the stage for a reaction to occur later
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