normocytic normochromic anemia - ANSWER Anemia of chronic disease
microcytic hypochromic anemia - ANSWER anemia characterized by small,
pale red blood cells that lack adequate hemoglobin to carry oxygen; can be
caused by deficiency of iron or vitamin B6
,- Thalassemias
S/S of pernicious anemia - ANSWER glossitis, paresthesia, loss of vibratory
sense, loss of fine motor, + rhomberg, +babinski
- splenomegaly
Testing for pernicious anemia - ANSWER Anti-IF and Anti-parietal cell
antibodies
-Schilling test to differentiate pernicious anemia from isolated B12 deficiency
Other causes of B12 deficiency that are NOT pernicious anemia - ANSWER
-Metformin
-Etoh
-Diet
-Hemodialysis
-Tapeworms
-Malabsorption from GI surgeries
Lab Ranges for serum Folate - ANSWER <2ng/ml is diagnostic
if >4ng/ml can rule out folate deficiency
, Drugs that can cause folate deficiency - ANSWER -Methotrexate
-Pyrimethamine
-etoh
-phenytoin
-isoniazid
-birth control
s/s of folate deficiency - ANSWER -glossitis, mouth and tongue pain,
hyperpigmentation, weight loss, orthostatic hypotension
What kind of Anemia is iron deficiency anemia - ANSWER microcytic
hypochromic
MCV for iron deficiency - ANSWER <80
MCHC for iron deficiency - ANSWER <32
S/S of iron deficiency anemia - ANSWER Pica, dyspnea, mild fatigue, h/a,
palpitations, weakness, tachycardia, postural hypotension, pallor
- Cheilosis- cracking on side of mouth
-spoon shaped, brittle nails
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