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AHN 577 - Final Test With Complete Solution

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AHN 577 - Final Test With Complete Solution...

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  • September 24, 2024
  • 48
  • 2024/2025
  • Exam (elaborations)
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  • ahn 577 final test
  • AHN 577
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AHN 577 - Final Test With
Complete Solution

Anemia - ANSWER Reduction in one or more major RBC measurements or
RBC count

Male: Hgb < 13.5 or Hct <41%

Female: Hgb < 12 or Hct <36%

Pernicious Anemia - ANSWER Caused by lack of intrinsic factors (IF)
produced by parietal cells of the gastric mucosa; prevent Vit B12 absorption
and causes Vit B12 deficiency

Vitamin B12 Deficiency Anemia - ANSWER Deficient in hydrochloric acid or
pancreatic enzymes causing inability to metabolize Vit B12

Folic Acid Deficiency Anemia - ANSWER ↓RBCs and Hgb content caused by
impaired production r/t ↓ serum folate




Anemia of Chronic Dz (ACD) - ANSWER 1. Gradual onset anemia
accompanied by:

• Chronic infection or inflammation

• Acute/Chronic immune activation (Rheumatoid arthritis)

• CKD &/or ESRD

• Underlying malignancies

,• ? Severe trauma, DM and advanced age




2. Reduction of RBC production by bone marrow d/t:

• Abnormal iron metabolism and reduced absorption from GI tract

• Inability to ↑ erythropoiesis in response to anemia

• Decreased in production of erythropoiesis

• Shortening of red cell life-span




Thalassemia - ANSWER Inherited disorder resulting in defective production
of the globin portion of Hgb




Autoimmune disorder

Megaloblastic

Macrocytic

Normochromic - ANSWER Prenicious anemia indices




Megaloblastic & Macrocytic & normochromic - ANSWER Vit B12 Deficiency
anemia

Folic Acid Deficiency Anemia

Pernicious Anemia indices

,Hypochromic & Microcytic - ANSWER Iron deficiency Anemia and
Thalassemia indices




Normochromic & Normocytic sometimes Hypochromic & Mircrocytic -
ANSWER Anemia of Chronic dz (ACD)




Normochromic to hypochromic & Microcytic - ANSWER Thalassemia indices




Prevalence of Thalassemia - ANSWER Mediterranean, African, and Asian




Hgb - ANSWER Main component of RBC and the essential protein that
combines w/ and transports O2 to the body

Males: 13.5-18

Females: 12-16




Hct - ANSWER Measures % of volume of whole blood that is occupied by
erythrocytes: the amount of plasma to total RBC mass (RBC concentration)

Males: 40-54%

Females: 37-47%

, TIBC - ANSWER 250-450




S. Iron - ANSWER 50-150




MCV - ANSWER Average volume and size of individual erythrocytes.




MCV Levels - ANSWER Microcytic: <80

Normocytic: 80-100

Macrocytic: > 100




MCH - ANSWER Average amount and weight of Hgb contained in a single
erythrocyte

26-34 pg




MCHC - ANSWER Average Hgb concentration or proportion of each RBC
occupied by Hgb as a % (100 mL)




MCHC levels - ANSWER Hypochromic: < 32%

Normochromic: 32-36%

Hyperchromic: > 36%

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