Anthracycline (Daunorubicin, doxorubicin, and epirubicin) cardiac effects -
ANSWER-cardiomyopathy
Diagnostic test for pericardial effusion - ANSWER-Echo
Abnormalities of what electrolyte and what mineral interfere with cardiac
function? - ANSWER-Potassium and Calcium
What med can be used to protect heart against effects of doxorubicin - ANSWER-
Dexrazoxane
Spiral CT - ANSWER-Diagnostic test for pulmonary emboli
, D-DImer test - ANSWER-used to diagnose or rule out conditions that cause
hypercoagulability (inappropriate clotting)
DIC - ANSWER-Accelerated activation of the coagulation cascade. Clots form in
random places leaving the body open to bleeding without protection
Platelet count, Fibrinogen level, D Dimer, FDP Titer - ANSWER-Tests to diagnose
DIC
How to treat DIC - ANSWER-Treat underlying cause
What does FFP do? - ANSWER-Contains all of the clotting factors except
platelets. Used to supplement red blood cells when whole blood is not available
or to correct a bleeding problem of unknown cause. It is also used to correct DIC.
Most common cancer associated with DIC? - ANSWER-Leukemia, specifically
APL
Signs/Symptoms of DIC - ANSWER-bleeding from 3 unrelated sites
hypoxia
SOB
fever
mottled extremities
Causes of DIC - ANSWER-Delivery (of baby)
Infection
Cancer
How does Heparin help DIC? - ANSWER-Interferes with thrombin production.
Maintain PTT at 1-2 times the normal level (18-28 seconds)
S/S of septic shock - ANSWER-Fever
Tachycardia
Hypotension
Most common cause of sepsis - ANSWER-Gram (-) bacteria
DIC - ANSWER-Accelerated activation of the coagulation cascade. Clots form in
random places leaving the body open to bleeding without protection
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