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NURB 3150 Anti-Infectives Exam Latest Update
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NURB 3150 Anti-Infectives ExamLatest Update
Beta-Lactam abx - Answer Penicillins
Cephalosporins
Carbapenems
Monobactams (one ring)
Penicillin - Answer Watch out for Anaphlyactic reactions:
-Swelling of airway
-Urticaria
-Dyspnea
-Wheezing
-Hypotension
-Tachycardia
-Angioedema
Common AE:
-N/V/D
bactericidal - Answer Penicillins
Cephalosporins
Carbapenems
Monobactams
Vancomycin
Aminoglycosides
Fluoroquinolones
Metronidazole
30 min - Answer To monitor for allergy after injecting Penicillins how long do you wait to
,see if there is a reaction?
probenecid - Answer What drug can interact with penicillin and prolong penicillins
therapeutic effects?
Penicillins - Answer Implications:
-Monitor for Allergy- Wait 30 minutes after admin
-Prepare for anaphylaxis
-Monitor VS
-Monitor WBC count
-Monitor electrolytes
-Take oral doses with water (not juices) as acidic
fluids may nullify drug's antibacterial action
-Monitor patients for an allergic
reaction for at least 30 minutes after
administration
Penicillins - Answer Amoxicillin
Nafcillin
Ticarcillin-Clavulanate
Piperacillin
Cephalosporins - Answer Adverse Effects:
-Anaphylaxis (urticaria, pruritis, angioedema, airway swelling, angioedema, dyspnea,
hypotension)
-Steven-Johnson syndrome
-Thrombophlebitis (when given IV)
-N/V/D
Steven-Johnson syndrome - Answer red vesicular rash over body, often an adverse
effect with Cephalosporins and
ETOH - Answer What interacts with Cephalosporins and causes a disulfiram like
reaction that includes N/V, HA, and hypotension?
Warfarin - Answer An anticoagulant that may increase the anticoagulant effect and
, cause increased bleeding when used with Penicillin or Cephalosporins?
Thrombophlebitis - Answer burning pain and swelling at IV site
Cephalosporins - Answer Implications:
-Monitor VS
-WBC count
-Educate about disulfiram like rxn with ETOH
-Prepare for anaphylaxis
-Take with food to reduce GI problems
-Assess for penicillin allergy; may have cross allergy
-Give orally administered forms with food to
decrease GI upset, even though this will delay
absorption
-Some of these drugs may cause a disulfiram
(Antabuse)- like reaction when taken with alcohol
Cephalosporin (and Carbapenem) - Answer What other antibiotic has a cross-sensitivity
with Penicillin?
spectrum of action (potency) - Answer The higher the generation of the Cephalosporin
the higher the what?
Cephalosporins - Answer 1st: Cefazolin, Cephradine, Cephalexin
2nd: Cefaclor, Cefotetan
3rd: Ceftriaxone, Cefotaxime
4th: Cefepime
1st - Answer Generation of Cephalosporins that include:
Cefazolin, Cephradine, Cephalexin
2nd - Answer Generation of Cephalosporins that include:
Cefaclor, Cefotetan
3rd - Answer Generation of Cephalosporins that include:
Ceftraixone, Cefotaxime
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