NAPLEX antibiotics Exam Questions and Answers fully solved 100%
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Course
NAPLEX
Institution
NAPLEX
MIC -ANSWER- lowest drug concentration that prevents visibile microbial growth in 24 hours
gram (+) bacteria species -ANSWER- staph, strep, EC, clostridium, listeria
which antibiotics exhibit time-dependent killing? -ANSWER- penicillins, cephalosporins
how can you increase the killing of a...
what organisms do the penicillins cover? -ANSWER- mainly gram (+), some gram (-)
which penicillin is the DOC in acute otitis media? -ANSWER- amoxicillin
which penicillin has activity against PA? -ANSWER- piperacillin
which penicillins do not require renal dosing? -ANSWER- nafcillin
oxacillin
dicloxacillin
Does Amoxil suspension need to be refrigerated? -ANSWER- no - stable for 14 days at
room temperature
how do you need to take Pen VK? -ANSWER- on an empty stomach
what IV fluid is ampicillin only compatible with? -ANSWER- NS
what are the main penicillin drug interactions? -ANSWER- probenacid, allopurinol -
increased penicillin levels
may decrease levels of oral contraceptives
what type of killing do cephalosporins exhibit? -ANSWER- time-dependent
what are the first generation cephalosporins? -ANSWER- cefazolin and cephalexin
what organisms are every cephalosporin active against? -ANSWER- strep/staph and
GNR
which cephalosporins are active against PA? -ANSWER- cefepime and ceftazidime
cefazolin brand name? -ANSWER- Kefzol
cephalexin brand name? -ANSWER- Keflex
ceftriaxone brand name and generation? -ANSWER- Rocephin - 3rd gen
, cefuroxime brand name? -ANSWER- Ceftin, Zinacef
what is the lone 4th generation cephalosporin? -ANSWER- cefepime (Maxipime) - 1-2 g
Q8-12
what generation is ceftaroline (Teflaro) in? -ANSWER- 5th
what are the main side effects of cephalosporins? -ANSWER- seizures with
accumulation
increased LFTs
GI upset, diarrhea
bone marrow suppression
which cephalosporins DO NOT require renal dose adjustments? -ANSWER- ceftriaxone
(Rocephin) - 3rd generation
what are the main drug interactions of cephalosporins? -ANSWER- probenacid,
allopurinol - increased levels of cephalosporins
may decrease effectiveness of oral contraceptives
What type of killing do carbapenems exhibit? -ANSWER- time-dependent bactericidal
generic name for Primaxin? -ANSWER- imipenem / cilastatin
what organisms do the carbapenems cover? -ANSWER- everything
*ertapenem = no EC or PA
*no MRSA
Brand name for meropenem? -ANSWER- Merrem
Brand name for ertapenem? -ANSWER- Invanz
Brand name for Doripenem? -ANSWER- Doribax
can carbapenems be used in a PCN allergy? -ANSWER- NO
carbapenem drug interactions? -ANSWER- uricosuric agents (probenacid, allopurinol)
caution with seizures
MOA of flouroquinolones -ANSWER- inhibit bacterial DNA topoisomerase IV and inhibit
DNA gyrase
what type of killing to flouroquinolones exhibit? -ANSWER- concentration-dependent
bactericidal
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