MOA: interferes with the conversion of intermediate DNA fragments into
high-molecular-weight DNA gyrase
Used for UTI, sinusitis, pneumonia, skin, bone and joint infections
NI: tendonitis, do not take with vitamins/minerals reduce absorption
Labs: BUN/Cr/ Liver function
Epinephrine (Adrenalin)
Nonselective Adrenergic Agonists
MOA: Activates both alpha and beta receptors
Used for bronchospasm, cardiac arrest, and hypotension
NI: Caution with CAD, Caution with digoxin and beta-blocker
Vitals: BP Labs: blood glucose
, LOW dose: vasodilation via B2-vascuar receptors
High Dose: vasoconstriction via alpha receptors
Dopamine (Inotropin)
Nonselective Adrenergic Agonist
MOA: Acts on beta and alpha receptors causing vasoconstriction in blood vessels
Used for shock, increased perfusion, hypotension, septic shock
NI: IV site for extravasation
Vitals: BP Labs: for renal check BUN/Cr/ GFR
LOW dose: renal and mesenteric vasodilation
Dobutamine (Dobutrex)
Beta-1 Agonist
MOA: Positive inotropic effects
Used for bradycardia and increased HR
NI: monitor for IV for extravasation
Vitals: HR and BP
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