NURS 307 Integrating Mental Health and Addiction into Nursing(400+ Q&As)
7 views 0 purchase
Course
NURS 307 I
Institution
NURS 307 I
NURS 307 Integrating Mental Health and Addiction into Nursing(400+ Q&As)/NURS 307 Integrating Mental Health and Addiction into Nursing(400+ Q&As)/NURS 307 Integrating Mental Health and Addiction into Nursing(400+ Q&As)
NURS 307 Integrating Mental Health and
Addiction into Nursing
What does carrier proteins do? - correct answer They transport neurotransmitters across cell
membranes. Medications may block or inhibit this transport.
What is psychopharmacology? - correct answer - Subspecialty of pharmacology that includes
medications affecting the brain and behaviour used to treat psychiatric disorders including:
~ Antipsychotics, mood stabilizers, antidepressants,
antianxiety medications, stimulants
- It provides a basis for understanding specific biologic treatments of psychiatric disorders
What are the four sites of action? Or, what are the targets of medications? - correct answer -
Receptors
- Ion channels
- Enzymes
- Carrier proteins
What are the two types of action in receptors? - correct answer Agonist - same biologic action
Antagonist - opposite effect
What are the interactions with a receptor? - correct answer Selectivity: specific for a receptor
Affinity: degree of attraction
Intrinsic activity: ability to produce a biologic response once it is attached to receptor
Which drug facilitates GABA (gamma-aminobutyric acid) neurotransmitter in opening the
chloride ion channel? - correct answer Benzodiazepine
What are enzymes - correct answer - These catalyze specific biochemical reactions within cells
and are targets for some drugs.
,NURS 307 Integrating Mental Health and
Addiction into Nursing
Ex) Monamine oxidase
- These may be inhibited to produce greater neurotransmitter effect by medications from a
group of antidepressants.
What is monoamine oxidase? - correct answer It is an enzyme that breaks down most
bioamine neurotransmitters such as Norephinephrine, DA, and 5-HT (these neurotransmitters
are important in mental health disorders)
What are carrier proteins? - correct answer They transport neurotransmitters across cell
membranes. Medications may block or inhibit this transport.
What is the efficacy of a drug? - correct answer Efficacy is the maximum response achievable
from a drug. Effectiveness refers to the ability of the drug to produce a beneficial effect.
What is the potency of a drug? - correct answer A highly potent drug (e.g., fentanyl,
alprazolam, risperidone) evokes a given response at low concentrations, while a drug of lower
potency (meperidine, diazepam, ziprasidone) evokes the same response only at higher
concentrations. Higher potency does not necessarily mean more side effects.
What are target symptoms? - correct answer measurable, specific symptoms expected to
improve with treatment
What is drug toxicity? - correct answer Drug level exceeds therapeutic range
What is therapeutic index? - correct answer Ratio of a drug's toxic level to the level that
provides therapeutic benefits. High is safer than low.
What are the four components of pharmacokinetics? - correct answer absorption, distribution,
metabolism, excretion
,NURS 307 Integrating Mental Health and
Addiction into Nursing
What is absorption? - correct answer - Movement from the site of administration into the
plasma
What are the 3 forms of absorption? - correct answer Oral (tablet and liquid) - decreased
absorption
IM (intramuscular injection): short and long acting-schizophrenia
IV: rarely used
What is Bioavailability? - correct answer - A measure of the extent of drug absorption for a
given drug and route (from 0% to 100%).
- Amount of a drug that reaches systemic circulation unchanged
- Often used to compare one drug to another--usually the higher the bioavailability, the better
What is distribution? - correct answer - transport of a drug by the bloodstream to its site of
action
- It reflects how easy it is for a drug to pass out of the systemic circulation and move into other
types of tissues
How are psychiatric drugs distributed? - correct answer The blood brain barrier (most fat-
soluble)
Factors affecting distribution - correct answer - Amount of blood flow or perfusion within the
tissue
- How lipophilic (fat-loving) the drug is (easier to pass through BBB)
- Anatomic barriers, such as the blood-brain barrier, that the drug must cross
, NURS 307 Integrating Mental Health and
Addiction into Nursing
Metabolism - correct answer Process by which the drug is altered and broken down into
smaller substances (metabolites) that are usually inactive
Which organ is where most metabolism occurs? - correct answer Liver
What is excretion? - correct answer The elimination of drugs from the body either unchanged
or as metabolites. It is portrayed as half-life (t1/2)
Dosing - correct answer Administration of medication over time, so that therapeutic levels can
be achieved.
Steady State - correct answer It is when drug accumulates and plateaus at a particular level.
What is the rate of accumulation in steady state determined by? - correct answer Half-life
When is steady state achieved? - correct answer - when the rate of drug input is equal to the
rate of drug elimination
- about 5 half lives (5x the elimination half-life for a drug after a regular dosing started)
What are the two individual variation in drug effects? - correct answer Age and Ethnicity
(genetic makeup)
How does age influence drug effects? - correct answer - there is an alteration in gastric
absorption
- renal function is altered in very young and old
- liver metabolism decreases with age
What are the 4 phases of drug treatment? - correct answer 1) initiation - long acting IM?
The benefits of buying summaries with Stuvia:
Guaranteed quality through customer reviews
Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.
Quick and easy check-out
You can quickly pay through credit card or Stuvia-credit for the summaries. There is no membership needed.
Focus on what matters
Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!
Frequently asked questions
What do I get when I buy this document?
You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.
Satisfaction guarantee: how does it work?
Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.
Who am I buying these notes from?
Stuvia is a marketplace, so you are not buying this document from us, but from seller gradebooster. Stuvia facilitates payment to the seller.
Will I be stuck with a subscription?
No, you only buy these notes for $18.49. You're not tied to anything after your purchase.
