NURP-533-Week 1 Exam Study
Guide
Primary HTN - Answer Increase in cardiac output and peripheral vascular resistance
Not due to an underlying disease; due to risk factors
Secondary HTN - Answer Due to and underlying disease: OSA,aldosteronism, renal
disease, excess catecholamines, coarction of the heart, Cushings' syndrome, drug side
effects, diet side effects, hypothyroidism, hyperthyroidism
Renin-angiotensin-aldosterone system - Answer Overactive RAAS leads to retention of
sodium and water which then leads to increased vascular resistance
This can ultimately lead to arterial remodeling
* Stages of HTN * - Answer Normal BP: SBP < 120 and a DBP < 80
Stage 1: SBP 130-139 or DBP of 80-89
Stage 2: SBP > 140 or DBP > 90
HTN Diagnosis - Answer Two elevated BP levels on two separate occasions (usually 2
weeks apart)
If BP readings are contradictory, a 24-hour ambulatory BP test may be done
Initial work-up includes: H&P, CBC, UA, glucose, BUN, Cr, electrolytes, ECG, lipids,
TSH, (CMP)
Obesity Screening in Adolescents - Answer The USPSTF recommends that clinicians
screen for obesity in children and adolescents 6 years and older and offer or refer them
to comprehensive, intensive behavioral interventions to promote improvements in
weight status.
Obesity Definition - Answer BMI greater than or equal to 30
Weight Gaining Medications - Answer Diabetes Rx: glipizide, insulin
Antidepressants, Neuroleptics, and Seizure Rx: TCAs, amitriptyline, MAOIs, SSRI's,
Mirtazapine, Lithium, clozapine, olanzapine, risperidone, quetiapine, valproic acid,
carbamazepine, lyrica, gabapentin
Antihistamines: cyproheptadine
Hormonal Rx
, Cardiac Rx: beta blockers
* Topamax may make you lose weight *
Drug Therapy Initiation for Obesity - Answer Add on lifestyle management for those with
a BMI equal to or greater than 30 OR those with a BMI equal to or greater than 27 with
co-morbid condition such as DM, high cholesterol, or HTN
Dyslypidemia - Answer Abnormal levels of serum lipoproteins
Hypercholestremia - Answer Elevated levels of LDL
Hypertriglyceridemia - Answer Elevated levels of VLDL
Atherosclerosis - Answer ASCVD risk assessment should be completed before starting
pharmacological risk factors
Exercise: 150 minutes/week of moderate intensity exercise or 75 minutes/week of
vigorous exericse
First line therapy for patients with T2DM is metformin
Aspirin therapy should be used sparingly
Statin therapy is first line treatment
CAD Risk Factors - Answer Age
Gender
Race
Total cholesterol
HDL
BP
DM
Smoking
USPSTF Screening for Lipid Disorders - Answer Universal screening for those age 40-75
Treatment is suggested for those age 4-75 with elevated lipids AND one other risk factor
for CAD (LDL > 130, HDL > 40, DM, HTN, smoking, AND > 10% risk calculation on the test
Use moderate-high dose statins for those with a risk score of 7.5-10%
There are no specific LDL levels to reach; you at least what them to decrease their LDL
level by 50%