2024 NURS 251 PHARMACOLOGY
MODULE 1 EXAM WITH CORRECT
ANSWERS
pharmacology - CORRECT-ANSWERSthe study or science of drugs
drug - CORRECT-ANSWERSany chemical that affects the physiologic process
of a living organism
pharmaceutics - CORRECT-ANSWERSthe study of how various dosage forms
influence the way in which the drug effects the body
pharmacokinetics - CORRECT-ANSWERSthe study of what the body does to a
drug
pharmacodynamics - CORRECT-ANSWERSthe study of what a drug does to
the body
absorption - CORRECT-ANSWERSmovement of a drug from its site of
administration into the bloodstream
distribution - CORRECT-ANSWERStransport of a drug by the bloodstream to
its site of action
metabolism - CORRECT-ANSWERSbiochemical alteration of a drug into a
metabolite
cytochrome P-450 - CORRECT-ANSWERSlarge class of enzymes that play a
significant role in drug metabolism and drug interactions
bioavailability - CORRECT-ANSWERShow much of the drug is absorbed into
the bloodstream for use (1-100%)
excretion - CORRECT-ANSWERSdescribes the elimination of the drug from
the body
half-life - CORRECT-ANSWERSthe amount of time it takes for 50% of a given
drug to be removed from the body
, steady state - CORRECT-ANSWERSthe physiologic state in which the amount
of drug being excreted from the body is equal to the amount being absorbed
with each dose
agonist - CORRECT-ANSWERSdrug binds to the receptor; there is a response
partial agonist - CORRECT-ANSWERSdrug binds to the receptor but the
response is diminished
antagonist - CORRECT-ANSWERSdrug binds to the receptor; there is NO
response AND it prevents other agonists from binding
competitive antagonist - CORRECT-ANSWERSdrug competes with agonist and
if it binds there is no response
noncompetitive antagonist - CORRECT-ANSWERSdrug combines with
different parts of the receptor and inactivates it; agonist then has no effect
enzymes - CORRECT-ANSWERSdrugs can interact with these by inhibiting or
enhancing their action
nonselective interactions - CORRECT-ANSWERSdescribes drugs that don't
target a specific receptor or enzyme but rather target cell membranes and
various cell processes
factors that affect drug response - CORRECT-ANSWERSage, weight, sex,
genetic variation
as you age, absorption is _____ - CORRECT-ANSWERSdelayed
as you age, distribution is ____ - CORRECT-ANSWERSincreased
as you age, metabolism ____ - CORRECT-ANSWERSdecreases
as you age, excretion ___ - CORRECT-ANSWERSdecreases
incompatability - CORRECT-ANSWERSphysical changes that occur when
mixed with another drug prior to administration
additive effects - CORRECT-ANSWERSwhen the combined effect of two drugs
is equal to the sum of each on its own
synergism - CORRECT-ANSWERSwhen the combined effect of two drugs is
greater the sum of each on its own
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