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NAPLEX BBW Exam Questions and Answers 2024/2025( A+ GRADED 100% VERIFIED).
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NAPLEX BBW Exam Questions and Answers 2024/2025( A+ GRADED 100% VERIFIED).
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NAPLEX BBWRituximab - ANS Serious & potentially fatal infusion reactions (~1st infusion)
*Administered in clinic
PML due to JCV
HBV reactivation
SJS/TEN
NSAIDs - ANS All including ASA: gI risk (bleeds/ulcers). Elderly w/ Hx of GI bleed avoid
systemic steroids SSRIs or SNRIs
Non-ASA: Cardiovascular Risk (MI, stroke, CV disease) Increase with duration of use
CABG: C/I for treatment of perioperative pain
Mephyton (Vitamin K aka phytonadione) - ANS Severe ~ hypersensitivity reaction (e.g.
anaphylaxis)
Four Factor Prothrombin Complex Concentrate
(PCC, Kcentra) - ANS Arterial and venous thromboembolic complications
Enoxaparin
Rivaroxaban & Apixaban
Fondaparinux
Dabigatran - ANS Pt. receiving neuraxial anesthesias (epidural spinal) or undergoing spinal
puncture are at risk of hematomas and subsequent paralysis
Warfarin - ANS Major or fatal bleeding
Savaysa - ANS CrCl > 95mL/min has reduced efficacy in patients with nonvalvular A.Fib
Droxidopa - ANS Supine hypertension
(Used for neurogenic orthostatic hypotension)
All antipsychotics - ANS Increased mortality in elderly with dementia-related psychosis primarily
due to infection or stroke
Cisplatin (Platinol) - ANS 1. Ototoxicity
(Doses > 100mg/m2/cycle must be confirmed with prescriber)
2. If > 6 cycles higher risk of anaphylaxis-like-rxn
Dopamine antagonist: Promethazine - ANS DNU < 2yo due to risk respiratory depression
, Do not give intra-arterial or SC
Deep IM preferred
Clozapine
(Clozaril, FazaClo ODT, Versacloz suspension) - ANS AGRANULOCYTOSIS
Tachy<3, OH, syncope - must titrate slowly
Myocarditis and cardiomyopathy
Sz's. Start no higher than 12.5mg BID
*never rechallenge drug*
(Super effective but used third line due to those side effects. Causes the least EPS)
Dopamine antagonist: Droperidol - ANS QT PROLONGATION AND ARRHYTHMIAS
Dopamine antagonist: Metoclopramide - ANS TD that can be irreversible
Avoid using >12 weeks
PCN G Benzathine - ANS IV use can cause cardiorespiratory arrest & death
Aminoglycosides - ANS Nephrotoxicity
Ototoxicity
NMB
Respiratory paralysis
Fetal harm (Tobramycin)
*Avoid other neuro & nephrotoxic drugs
Quinolones - ANS Tendon inflammation &/or rupture
Peripheral neuropathy
CNS effects
Avoid use: Myasthenia gravis (may exacerbate muscle weakness)
Use last line 4:
Bacterial sinusitis
Exacerbation of chronic bronchitis
*Uncomplicated UTI
Telavancin
(Vibativ) - ANS Fetal risk
Nephrotoxicity: Increased mortality vs. vanco use
Tigecycline
(Tygacil) - ANS Increased risk of death
Chloramphenicol - ANS Serious & fatal blood dyscrasias
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