Beta blockers "olols" Metoprolol Propranolol Carvedilol
Pharmacodynamics of beta blockers -prevent beta-adrenergic receptors from being stimulated -decrease the oxygen demands of heart and decrease angina -causes blockade in myocardium/electrical conduction Decrease hr Vasodilator -reduces release...
Pharmacodynamics of beta blockers ✅-prevent beta-adrenergic receptors from being
stimulated
-decrease the oxygen demands of heart and decrease angina
-causes blockade in myocardium/electrical conduction
Decrease hr
Vasodilator
-reduces release of renin
Overall role of beta blocker ✅slow hr by suppressing the sa node which slows the
speed of conduction through the av node
-decreases the force of contraction
-decrease bp
-reduce contractility
How do beta blockers work ✅block epinephrine from binding to the beta receptors
which causes the heart to beat slower and reduces blood pressure, lowering bp
Beta blocker prototype drug ✅metoprolol (lopressor)
Side effects of beta blockers ✅bradycardia
Bronchoconstriction
Decreased cardiac output
Av block
Hypotension
Class i ✅lidocaine
Nursing interventions beta blockers ✅-do not abruptly stop medication
-monitor blood pressure, pulmonary wedge pressure, and cardiac rhythm and
conduction (check ekgs)
Metoprolol ✅treatment of hypertension, angina, controlled congestive heart failure
-do not abruptly stop medication
-goal: decrease workload on heart and its oxygen need
, Goal of anti-hypertension medications ✅affect/change one or more mechanisms that
affect peripheral resistances
Starting medication for high bp ✅diuretic
Loop diuretics ✅furosemide (lasix)
Bumetanide
Torsemide
-always have ide
Furosemide (lasix) ✅loop diuretic
Treats peripheral and pulmonary edema and hypertension by inhibiting the reabsorption
of sodium, chloride, and water in the ascending loop of henle
Pharmacodynamic of loop diuretics ✅block reabsorption of sodium/chloride and
prevent reabsorption of water in loop of henle
-decrease blood volume
-excretion of water and sodium
Side effects of loops diuretic ✅ototoxicity/tinnitus (hearing problems), dehydration,
electrolyte imbalance, hypotension, hypokalemia
Hypokalemia ✅deficient potassium in the blood (normal 3.5-5)
-issues are generally cardiac and dysrhythmia related
Thiazide diuretics ✅hydrochlorothiazide (hctz)
-always have thiazide in them
Pharmacodynamics of thiazide diuretic ✅block reabsorption of sodium/chloride and
prevent reabsorption of water in distal convoluted tubule
Side effects of thiazide diuretic ✅dehydration
Hypokalemia
Hypotension
Hyperglycemia
Spironolactone ✅potassium sparing diuretic
Manage edema and hypertension by inhibiting transport of sodium in distal convoluted
tubules, decreases sodium and water reabsorption but increases potassium retention
Pharmacodynamics potassium sparing diuretics ✅block action of aldosterone which
results in potassium retention and excretion of na and h2o
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