Definition 1 of 65
Progesterone
Medroxyprogesterone
Norethrindrone
Megestrol Acetate
Most used in oral contraceptives & for HRT
Some generations have been developed to
- Address mood change
- Break through bleeding
- Sensitivity to progesterone agents
Progesterones
Pregnancy and progestins
Progestin Administration
Progestin Adverse Reactions
,Definition 2 of 65
Gynecomastia
Reduced sperm levels
Ance
Baldness
Decrease libido
Depression
Headache
Scrotal pain
Goin pain
Changes in Urination
Priapism (A sustained erection)
,Definition 3 of 65
Most reactions are dose-related
Most are seen in oral contraceptives
Cardiovascular + hematological MI
HTN
Alteration in clotting factors
Thromboembolism
(Leg pain, visual disturbances, + severe headache)
Elevation of systemic BP
Gallbladder disease
Irregular bleeding
, Definition 5 of 65
Once or twice weekly application
Also have skin irritation 20-40%
Progestins Precautions
Refer to endocrinologist
Vaginal Instillation
Transdermal Formulations
Definition 6 of 65
1:10
Dose of estrogen for contraception is higher than the dose needed for replacement therapy
Potency ratio of replacement estrogens to contraception estrogens
The dosage of testosterone compared to estrogen for contraception
The effectiveness of estrogen in treating menopause symptoms
The side effects of estrogen in male patients
Definition 7 of 65
Progesterone is category D
Norethindrone acetate is X
Progesterone gel is used to support embryo implantation & maintain pregnancies.
Lactation may be enhanced by Medroxyprogesterone, dont know what effects are on infants
Pregnancy and progestins
Clinical use Androgens
Progestin Adverse Reactions
Progestins Contraindications
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