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Exam (elaborations)

NR 566 WEEK 1 QUESTIONS AND ANSWERS

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  • NR 566
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  • NR 566

NR 566 WEEK 1 QUESTIONS AND ANSWERS

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  • September 20, 2024
  • 125
  • 2024/2025
  • Exam (elaborations)
  • Questions & answers
  • NR 566
  • NR 566
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131 Multiple choice questions

Term 1 of 131
Penicillin distribution

Ampcillin/sulbactam (unasyn)
amoxicillin/clavulanate (augmentin)
piperacillin/tazobactam (zosyn)

check for interactions of other drugs the patient is taking as tetracycline interacts with
many drugs including digoxin

alternative to penicillin G in pts with penicillin allergy

treatment of choice for diphtheria

-Well distributed to most body tissues
-Penetration to CSF and eye tissues poor in absence of inflammation

Term 2 of 131
fluoroquinolone black box warning

increased risk of gastrointestinal bleeding

enhanced effectiveness of other antibiotics


tendon rupture and exacerbation of muscle weakness in patients with myasthenia gravis

no significant risks associated with their use

Term 3 of 131
2nd-5th generations cephalosporins susceptible pathogens

broad spectrum gram positive and gram negative bacteri

only anaerobic bacteria and certain protozoa


narrow spectrum targeting only gram positive bacteria


specific strains of viruses and fungi

,Term 4 of 131
4th generation cephalosporins

Ceftaroline (teflaro)


Cephalexin (keflex)

Cefepime (Maxipime)


Ceftriaxone (rocephin)

Term 5 of 131
how do carbapenems effect emergence of resistance

teeth- yellow/brown discoloration, hypoplasia of enamel

bones-if taken while pregnant will suppress growth of long bones of infant

IV due to poor GI absorption


except for CDIFF infections which it can be given orally

carbapenems are extremely broad-spectrum and effective at killing both gram positive
and gram negative bacilli which can lead to emergence of resistance which is actually a
global healthcare problem that is being talked about

reserve prescribing to only patients who cannot be treated with a more narrow-
spectrum agent

,Term 6 of 131
if a patient has a severe allergy to penicillins what is an appropriate drug alternative

Naficillin
oxacillin
dicloxacillin

Piperacillin

Imipenem
meropenem
ertapenem
doripenem


NOT CEPHALOSPORINS
vancomycin
erythromycin
clindamycin

Term 7 of 131
Vancomycin MOA

skin and soft tissue infection

inhibits cell wall synthesis
-bacteriocidal

inhibits protein synthesis, bacteriostatic

inhibit cell wall synthesis; bactericidal

, Term 8 of 131
bacteriostatic drugs

Azithromycin
Clarithromycin
Erythromycin (oldest)

antibiotics that do not actually kill bacteria but rather inhibit bacterial proliferation while
the hosts immune system does the killing

piperacillin


clindamycin
macrolides
sulfonamides
tetracyclines

Term 9 of 131
Penicillin/Beta lactamase combinations

Inhibit protein synthesis (bacteriostatic)

Ceftaroline (teflaro)

Ampcillin/sulbactam (unasyn)
amoxicillin/clavulanate (augmentin)
piperacillin/tazobactam (zosyn)


calcium supplements
milk products
iron supplements
magnesium laxatives
most anatacids

Term 10 of 131
what is the empiric therapy of choice for CAP

kill bacteria without harming host tissue


combinations beta-lactam plus macrolide

cephalosporins

kill bacteria without harming host tissue

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