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AAMC FL 2 BB questions and answers graded A+ 2024/2025
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AAMC FL 2 BB questions and answers graded A+ 2024/2025
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AAMC FL 2 BBThe facts inside the passage shows that in mice CRY1 most likely influences XPA with the aid
of:
A.Activating XPA protein interest.
B.Activating translation of XPA-encoding transcripts.
C.Repressing replication of the XPA-encoding gene.
D.Repressing transcription of the XPA-encoding gene.
Passage: the nucleotide excision restore device (NER) recognizes, removes, and replaces
segments of DNA strands that incorporate CPDs and (6-four) PPs. Figure 1 suggests how
mouse pores and skin tiers of XPA (a harm-popularity and charge-restricting aspect in NER) and
clock regulatory protein CRY1 - ANSD. The graph suggests that whilst CRY1 is up, XPA ranges
are down. So it's miles going to depress the activity. XPA is said to be a harm-recognition and
rate proscribing element in NER, consequently you could deduce that it is going to be an
enzyme=protein=transcription.
Which cells harvested from adult mice had been most likely used because the particularly
proliferative benchmark in the experiment that generated the data shown in Figure 3?
A.Adipocytes
B.Cardiac muscle cells
C.Gastrointestinal epithelial cells
D.Neurons - ANSKey phrase right here is proliferative. Proliferative cells develop or multiply by
means of unexpectedly generating new tissue, elements, cells, or offspring. This happens A
LOT inside the stomach.
POE:
A- no. Mature adipocytes do not divide
B- cardiac MUSCLE cells do now not divide once matured.
D- neurons NEVER divide. Once you lose a neuron, it's long past forever.
After a phase of a DNA strand containing a UVR-brought on lesion is removed and
resynthesized, the newly synthesized strand is rejoined to the the rest of the DNA strand by way
of what kind of bond?
A.Disulfide
B.Hydrogen
C.Peptide
D.Phosphodiester - ANSDna is joined collectively by means of phosphodiester bonds :)
, Which image indicates an example of a cyclobutane pyrimidine dimer? - ANSRemember:
pyrimidines are one ring. Purines are two jewelry. Dimer=2 fused together.
AlP exposed to an aqueous answer wherein pH range will bring about the most important
amount of PHOSPHINE manufacturing?
A.PH < four
B.Four < pH < 7
C.7 < pH < 10
D.PH > 10
equation: AIP + 3H+ ---->AI+ + 3PH3 - ANSaccording to lechatlier's principle, whilst you boom
the 3h+ (making PH hella acidic) the equation goes to shift to the right and make more
phosphine.
Based at the passage, which amino acid will most possibly react with phosphine?
A.Met
B.Cys
C.Ser
D.Thr
passage: It is idea that phosphine reacts with important sulfhydryl organizations - ANScysteine
has sulfhydryl agencies and can make disulfide bonds. Methionine is the other amino acid that
is sulfur containing, but cannot make disulfide bonds. Therefore cysteine is an appropriate
answer.
When researchers decided the full mobile attention of ATP in AlP-exposed rat liver cells, they
found the awareness to be identical to the manipulate price. Which end approximately the
metabolic state of the cellular is fine supported with the aid of those records?
A.Glycolytic flux is elevated after AlP treatment.
B.Glycolytic flux is reduced after AlP remedy.
C.Citric acid cycle flux is improved after AlP treatment.
D.Citric acid cycle flux is decreased after AlP remedy.
Passage: It turned into located that AlP exposure led to a 65% lower in ATP ranges and a forty
eight% lower inside the fee of ATP synthesis. In addition, the impact of AlP on the hobby of
three ETC complexes changed into decided (Table 1). The activities of these complexes had
been determined independently of each other. - ANSMitochondrial ATP synthesis has been
reduced based on the passage and the statistics inside the table. Therefore, most of the app
with a view to be made will should be in the cytosol outside of the mitochondria.
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