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GMS 6530 Hyperlipidemia Exam With Actual Questions And Verified Detailed Answers By Experts Latest Update $10.99   Add to cart

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GMS 6530 Hyperlipidemia Exam With Actual Questions And Verified Detailed Answers By Experts Latest Update

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GMS 6530 Hyperlipidemia Exam With Actual Questions And Verified Detailed Answers By Experts Latest Update...

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  • September 19, 2024
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  • 2024/2025
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  • GMS 6530 Hyperlipidemia
  • GMS 6530 Hyperlipidemia
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GMS 6530 Hyperlipidemia Exam With Actual Questions And Verified
Detailed Answers By Experts Latest Update


Chylomicrons - Answer - largest

- primarily triglycerides

- short life span

- degraded by LPL



VLDL - Answer - primarily triglycerides



IDL - Answer - cholesterol

- triglycerides



LDL - Answer - cholesterol

- bad



HDL - Answer - apolipoproteins

- little cholesterol

- good



LPL - Answer - lipoprotein lipase

- degrades lipoproteins to free fatty acids

- reduces triglyceride levels



LDL receptors - Answer - decline with age

- located in liver

, - regulate plasma cholesterol levels



Statins - Answer - HMG-coA reductase inhibitors

- or's & ol's

- reduce cholesterol synthesis

- most effective in reducing LDL

- work in hepatocytes



Statins indirect action - Answer - increase LDL receptors > increasing extraction of LDL
by liver, decreasing plasma concentration

- small decrease in VLDL (triglycerides) & HDL

-

Statin use - Answer - hypercholesterolemia (increased LDL)

- mixed hyperlipidemia (increased LDL & VLDL)

- first line after MI



Statin side effects - Answer - risk of diabetes increased

- cognative impairment-usually short term

- hepatitis-increase in hepatic enzymes

- myalgia-muscle pain

- discontinue if creatine phosphokinase is elevated or myopathy-rhabdo or
myoglobinuria



Niacin - Answer - vitamin B3-nicotinic acid

- inhibits lipolysis in adipose > decreasing FFA supply to liver & VLDL synthesis

- increases LPL activity > lowering plasma VLDL conc.

- increases plasma HDL

mixed hyperlidemia

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