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Adv. Pharm NURS 8024 Week 1 questions well answered to pass
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Adv. Pharm NURS 8024 Week 1 questions well answered to pass
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Adv. Pharm NURS 8024 Week 1Pharmacokinetics - correct answer ✔✔what the body does to the drug
Pharmacodynamics - correct answer ✔✔what the drug does to the body
Toxicology - correct answer ✔✔The undesirable effects of chemicals on living systems
Pharmacotherapeutics - correct answer ✔✔dynamic that achieves the desired therapeutic effect of the
drug without causing other undesirable effects
Legend drugs - correct answer ✔✔another name for prescription drugs
Pharmacogenomics - correct answer ✔✔the study of genetically determined variations in the response
to drugs
Pharmacologic Agonist - correct answer ✔✔agent binds to and activates the
receptor - directly or indirectly causing an effect, full or partial agonists
Pharmacological Antagonist - correct answer ✔✔Agent binds to receptor-completes with other
molecules and prevents binding by other molecules-it inhibits other molecules from binding
Pro-drug - correct answer ✔✔An inactive percursor chemical-must be abosorbed and distributed and
converted to the active form of the drug by biologic processes.
What is ADME? - correct answer ✔✔Absorption
Distribution
Metabolism
Elimination
, Absorption - correct answer ✔✔entry of pharmacologic agent into plasma
Distribution - correct answer ✔✔agent leaves the bloodstream and distributes to interstitial and
intracellular fluids
Metablosim - correct answer ✔✔chemical processes that occur to make the drug useful in the
bloodstream--done by the liver, kidney, or other tissue
Ellimination - correct answer ✔✔Leaving the body-via urine, bile, feces, lungs, sweat, breast milk
2 Major Administration Routes - correct answer ✔✔1. Enteral -most common, easy, cheap-BUT drug
absorption pathways can be complicated
2. Parenteral-IV, fast, more expensive, once in-cannot get back
Enteral drug administration - correct answer ✔✔oral, sublingual, rectal
drug absorption pathways complicated
**First-pass metabolism can limit the amount of drug that enters systemic circulation
influenced by food and other drugs
What is first pass metabolism? - correct answer ✔✔The concentration of drug is greatly reduced BEFORE
reaching systemic circulation. This mainly involves liver enzymes, but also includes gastric enzymes, gut
wall enzymes, and bacterial enzymes. Bioavaliability is reduced.
https://www.youtube.com/watch?v=BQQns7RAUzA
Parenteral drug administration - correct answer ✔✔-IV, IM, SubQ
- More control over actual dose of drug
- Directly into systemic circulation-bypass first pass metabolism
- used for drugs poorly absorbed by GI
-Rapid onset of action
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