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MICR 270 Final Exam Study Guide| 100% Pass Guaranteed
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MICR 270 Final Exam Study Guide|100% Pass Guaranteed
autoimmunity - Answer the inability to distinguish between self-antigens and foreign
antigens, immune system reacts to its own cells
organ specific autoimmune diseases - Answer IR is directed to an antigen that is
unique to a single gland or organ
ex: Graves disease- hyperthyroidism
systemic autoimmune diseases - Answer IR is directed towards a broad range
of antigens that are characteristic towards a large number of organs or tissues
ex: Rheumatoid arthritis (IgM and IgG)
treatment of autoimmune - Answer immunosuppressants
Type I hypersensitivity - Answer immediate or anaphylactic hypersensitivity,
IgE mediated
ex: asthma, eczema, hives, rhinitis
, Type II hypersensitivity - Answer antibody mediated/cytotoxic hypersensitivity, IgG IgM
mediated
ex: drug induced hemolytic anemia or transfusion reaction
Type III hypersensitivity - Answer immune complex mediated hypersensitivity,
mediated by complement proteins, immune complexes and neutrophils
ex: serum sickness
Type IV hypersensitivity - Answer cell mediated or delayed hypersensitivity, mediated
by CD8+, CD4+, macrophages only one thats not mediated by antibodies!!
ex: Crohn's disease, ulcerative colitis, contact dermatitis
How do allergens produce an allergic response? - Answer allergen induces a humours
réponse and secretes excessive amount of IgE antibodies. Secondary exposure
initiates degranulation of basophils and mast cells leading to vasodilation and smooth
muscle contraction.
What does flow cytometry measure? - Answer The physical and chemical
characteristics/complexity of a cell, as well as specific cells and their proportions
what does ELISA measure? - Answer presence of an antibody or antigen, as well
as hormones, peptides or proteins
what can flow cytometry be used for? - Answer diagnose cancer through detection
of DNA aneuploidy, cell cycles and immunophenotypes
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