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Hemostasis

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Following slides include Hemostasis and how blood functions help our body with factors affecting Hemostasis and in depth understanding of function of blood.

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  • September 19, 2024
  • 31
  • 2024/2025
  • Class notes
  • Alishba
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2004alishkhan
HEMOSTASIS

,• It is the prevention of blood loss
• Whenever a blood vessel is severed or ruptured , following
mechanisms takes place to arrest the bleeding
1) Vascular spasm
2) Platelet plug formation.
3) Blood coagulation
4) Growth of fibrous tissue into the blood clot to close the hole
of the vessel

,HEMOSTASIS:
BV Injury

Tissue
Neural Factor



Blood Vessel Platelet Coagulation
Constriction Activation Activation
Primary hemostatic
plug
Reduced
Plt-Fusion Thromibn
Blood ,
flow
Fibrin

Stable Hemostatic Plug

, 1) VASCULAR SPASM:
• Trauma to the blood vessel causes the smooth muscles in the
vascular wall to contracts.
• Constriction reduces the blood flow from the injured vessel
• Vascular constriction results from
a) Local myogenic mechanism
b) Factors released from the traumatized vessel & platelets.
c) Nervous reflexes.
• Constriction lasts for many minutes to hours by which time
the process of platelet plug & blood coagulation takes place.

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