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Stupid PCOA-like Exam (P1 only) Questions And 100% Correct Answers
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Stupid PCOA-like Exam (P1 only) Questions And 100%Correct Answers
Different levels of protein structures
- Primary: sequence of amino acids
- Secondary: folding of the primary structure to form alpha helices or beta sheets/turns;
stabilized by hydrogen bonding
- Tertiary: self-assembly of secondary structures
- Quaternary: contains 2+ polypeptide chains
The peptide Ala-Glu-Gly-Ala-Leu has:
A. Disulfide bridge
B. 5 peptide bonds
C. 4 peptide bonds (between 5 Amino Acids)
D. No free carboxyl group
E. 4 ester bonds
Four peptide bonds (between 5 Amino Acids)
Skip 10 seconds ahead Unmute 0::15 Full screen Brainpower Read More Amino
acids most often occurring in B-turns are:
A. Ala and Gly
B. Hydrophobic
C. Pro and Gly
D. With ionized side chains
E. Pairs of Cys
Pro and Gly
In an a-helix, the hydrogen bonds
A. Occur largely between electronegative atoms of the side chains
,B. Occur only between some of the amino acids of the helix
C. Occur only near the amino and carboxyl terminal of the helix
D. Are approximately perpendicular to the helix axis
E. Are approximately parallel to the helix axis
Are approximately parallel to the helix axis
Regarding a folded protein in solution, which of the following is most likely to be true of a
contiguous sequence of hydrophobic amino acids?
A. Alpha helix
B. Beta sheet
C. Part of an active site
D. On the surface of the protein, exposed to the aqueous solution
E. On the interior of the protein, buried away from the aqueous solution
On the interior of the protein, buried away from the aqueous solution
Hemoglobin and Myoglobin are structurally homologous. Which statement is most
CORRECT?
A. This means that they have nearly identical amino acid sequences
B. Structural homology implies identical function
C. Structural homology only implies that the two proteins have similar folds
D. All proteins with high a-helix content have structural homology 21.
E. Myoglobin is actually a hemoglobin monomer
Structural homology only suggests that the two proteins have similar folds
Active site of enzymes- very specific to the substrates that it will bind with.
, 3D in shape & usually located inside the enzyme folds
Upon the binding of the substrate to it, there would be a 3D conformational change of
the enzyme and would either activate or inactivate the enzyme.
Michaelis-Menten equation
v=(vmax [S])/ (Km+[S])
A mathematical expression which describes quantitatively the relation between the rate
of the enzyme catalyzed reaction and the substrate concentration
Small Km= high affinity
Nutrient Utilization
The way the nutrients from food are utilized by the body
Macronutrients (carbs, fats, & proteins) are oxidized either for generating ATP, or for
producing the building blocks to support cell growth and repair.
creatinine clearance equation
- [(140-age)(Ideal body weight)] / 72(Scr)
- multiply the answer by 0.85 for women
IBW equation
- Males: IBW = 50 kg + 2.3 kg for each inch over 5 feet.
- Females: IBW = 45.5 kg + 2.3 kg for each inch over 5 feet.
adjusted body weight
IBW + 0.4(ABW-IBW) formula for converting mg to meq
meq = [mEq x formula weight]/ valence formula for converting meq to mg
meq =[mg x valence] / formula weight
Intern laws per the state of Oklahoma
Intern : preceptor ratios 1:1
(or 2:1; College of Pharmacy Faculty may precept 2 interns at a time
An intern may not be on duty in any capacity without a licensed pharmacist preceptor on
site & supervising the intern
- An intern shall not sign a prescription
- An intern shall not supervise a technician
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