NURS 617 PHARM EXAM 1, 2 AND FINAL EXAM LATEST VERSIONS (JEAN GENZALE PHARMACOTHERAPEUTICS, RATED A+/ GUARANTEED PASS
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Course
Nursing pharmacology
Institution
Nursing Pharmacology
Pharmacogenomics - ANSWER the study of genetically determined variations in the response to drugs
Pharmacokinetics - ANSWER The way the body processes drugs. Involves 4 processes of:
-absorption
-distribution
-metabolism
-excretion
Drug clearance - ANSWER The process of metabolism and excreti...
NURS 617 PHARM EXAM 1, 2 AND FINAL EXAM
LATEST VERSIONS (JEAN GENZALE
PHARMACOTHERAPEUTICS, RATED A+/
GUARANTEED PASS
Pharmacogenomics - ANSWER the study of genetically determined variations in the response to drugs
Pharmacokinetics - ANSWER The way the body processes drugs. Involves 4 processes of:
-absorption
-distribution
-metabolism
-excretion
Drug clearance - ANSWER The process of metabolism and excretion/
The disappearance of the drug from the patient's serum
Absorption - ANSWER The process by which drug molecules move from their site of administration,
across one or more cell membranes, in order to gain entry to the blood
Driving force of absorption - ANSWER Concentration gradient = Concentration on either side of the
membrane
Concentration Gradient - ANSWER Passive diffusion- from high concentration to low concentration. Does
NOT require energy
Routes of drug administration that do NOT involve the absorption process - ANSWER -IV
, -Intraarterial
Absorption: Fastest to slowest drug formulations - ANSWER FASTEST
-liquids
-suspensions
-powders
-capsules
-tablets
-enteric coated tablets
-sustained release tablets
SLOWEST
Factors that determine the rate and extent of drug absorption - ANSWER -solubility (or dissolvability) of
the drug
-physical properties of the drug
-area of absorptive surface
-blood supply at absorptive surface
-length of time of contact with absorptive surface
Cell membranes are composed of lipids. --> Fat-soluble molecules cross the membrane easier than
water-soluble. What are fat soluble molecules called? - ANSWER Non-ionized
Non-polarized
***Acidic
Water soluble molecules - ANSWER Ionized
Polarized
***basic
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