What is a dry powder inhaler? A. A device used to aerosolize and deliver a solid drug product B. A device used to aerosolize and deliver a pharmaceutical suspension C. A device used to aerosolize and deliver a pharmaceutical solution A. A device used to aerosolize and deliver a solid drug product
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NUR 514 Exam 2 Questions and Correct
Answers
What is a dry powder inhaler?
A. A device used to aerosolize and deliver a solid drug product
B. A device used to aerosolize and deliver a pharmaceutical suspension
C. A device used to aerosolize and deliver a pharmaceutical solution ✅A. A device
used to aerosolize and deliver a solid drug product
Which of the following is the primary advantage of local pulmonary drug delivery
compared to oral drug delivery?
A. Reduces systemic drug exposure
B. Rapid absorption into systemic circulation
C. Increases bioavailability by avoiding first-pass metabolism ✅A. Reduces systemic
drug exposure
Where are drug particles with a diameter between 2 to 5 microns most likely to deposit?
A. Oropharynx
B. Alveoli
C. Bronchioles ✅C. Bronchioles
What is a metered dose inhaler?
A. A device that uses an external energy source to disperse and deliver drug solid
solutions and suspensions
B. A device that uses a pressurized system to disperse and deliver drug solutions and
suspensions
C. A device used that uses breath-power to aerosolize and deliver solid solutions and
solid suspensions ✅B. A device that uses a pressurized system to disperse and
deliver drug solutions and suspensions
Systemically administered pulmonary drugs are absorbed in which part of the lung?
A. trachea
B. bronchiole
C. alveoli ✅C. alveoli
Which of the following is a disadvantage of nebulizers?
A. propellant is required for dispersion
B. long treatment time compared to inhalers
C. depends on patient inspiratory force
D. requires coordination of inhalation and actuation ✅B. long treatment time
compared to inhalers
When administered via the intranasal route, what is the deposition site for dry powder
particles with diameters less than 1 micron?
, A. trachea
B. nasal cavity
C. alveoli
D. outside of the body due to exhalation ✅D. outside of the body due to exhalation
Why are viscosifying agents added to intranasal dosage forms?
A. To increase the drug residence time at the site of absorption
B. To increase the permeability of the nasal epithelium
C. To ensure sterility of multidose dosage forms ✅A. To increase the drug residence
time at the site of absorption
What is the "dead volume" in a nebulizer?
A. volume of residual drug solution that could not be nebulized during administration
B. volume of drug solution that is collected on the baffle during administration
C. minimum volume of drug solution required to prevent drug-induced cytotoxicity of the
respiratory epithelium
D. minimum volume of drug solution required to kill bacteria in the respiratory tract
✅A. volume of residual drug solution that could not be nebulized during administration
What the primary route of transport of peptide drugs across the nasal epithelium?
A. paracellular transport
B. transcellular transport
C. transcytosis ✅C. transcytosis
What is a passive dry powder inhaler?
a. An electrically powered device used to deliver solid aerosols
b. A breath-powered device used to deliver solid aerosols
c. An electrically powered device used to deliver liquid aerosols
d. A breath-powered device used to deliver liquid aerosols ✅b. A breath-powered
device used to deliver solid aerosols
What is the optimal site of drug absorption for systemic delivery via the pulmonary
route?
a. trachea
b. bronchi
c. terminal bronchioles
d. alveoli ✅d. alveoli
Which of the following is the primary advantage of local pulmonary drug delivery
compared to oral drug delivery?
a. Bypass first-pass metabolism
b. Reduces systemic drug exposure
c. Rapid absorption into the circulation ✅b. Reduces systemic drug exposure
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