TITLE: EMILLYCHARLOTTE 2024/2025 ACADEMIC PERIOD
OWNER: EMILLYCHARLOTTE
COPYRIGHT STATEMENT: ©2024 EMILLYCHARLOTTE. ALL RIGHTS RESERVED
FIRST PUBLISHED: SEPTEMBER 2024
NSG 170 Final Exam Questions and
Answers | 100% Pass
What class is filgrastim (Neupogen) - Answer✔️✔️-colony stimulating factors
What is gene therapy? - Answer✔️✔️-The use of genes to treat/ prevent disease . Only
available via clinical trials. Technology replaces abnormal genes for healthy genes and
can repair abnormal gene cells or alternating the amount of genes that can be activated.
They kill cancer cells by inserting genes that boost the immune system to destroy the
cancer.
What class is epoetin alfa (Epogen) - Answer✔️✔️-Erythropoiesis-stimulating agents
What is epoetin alfa (Epogen) used for? MOA - Answer✔️✔️-Used to counteract the
effects of chemotherapy. Stimulates the production and release of reticulocytes from
bone marrow. Has anemic affects and treats a wide variety of cancer.
What is filgrastim (Neupogen) used for? MOA - Answer✔️✔️-Reduces the time for
neutrophil recovery and duration of fever in patients undergoing chemotherapy to treat
AML. Binding to and stimulating immature neutrophils to invade and differentiate, also
activates mature neutrophils
What class is Ondansetron (Zofran) - Answer✔️✔️-Serotonin (5-HT3) Receptor
Antagonist (Antiemetic)
,TITLE: EMILLYCHARLOTTE 2024/2025 ACADEMIC PERIOD
OWNER: EMILLYCHARLOTTE
COPYRIGHT STATEMENT: ©2024 EMILLYCHARLOTTE. ALL RIGHTS RESERVED
FIRST PUBLISHED: SEPTEMBER 2024
What does Ondansetron (Zofran) do? MOA - Answer✔️✔️-Blocks 5-HT3 receptors in the
brain and peripheral nervous system.
Nursing Considerations for Ondansetron (Zofran) - Answer✔️✔️-If the patient is taking
frequently, monitor liver function and clotting ability closely.Monitor patient for serotonin
syndrome(s/s are mental status changes,tachycardia, diaphoresis,flushing, n/v, tremors,
and muscle rigidity). Correct any electrolyte imbalances before starting drug therapy to
reduce risk of cardiac arrhythmias.
Monitor EKG and cardiac function in patients who have a cardiac history.
What class is metoclopramide (Reglan) - Answer✔️✔️-prokinetic agent (Antiemetic)
What does metoclopramide (Reglan) do? MOA - Answer✔️✔️-Stimulates motility of the
upper GI tract, blocks dopamine receptors at the chemoreceptor trigger zone. Oral, IV,
IM, and intranasal
What are the nursing considerations for metoclopramide (Reglan) - Answer✔️✔️-
Administer 30 minutes before each meal and at bedtime. Monitor liver function and
WBC counts Monitor bowel sounds Monitor for parkinsonian extrapyramidal adverse
effects that cause involuntary movements of face, tongue, and extremities.
What are the contraindication for metoclopramide (Reglan) - Answer✔️✔️-Avoid giving
with other CNS depressants, can increase blood glucose level
What class is dronabinol (Marinol) - Answer✔️✔️-Cannabinoids (Antiemetic)
What does dronabinol (Marinol) do? MOA - Answer✔️✔️-Potentiates the activity of
cannabinoid receptors in the brain
,TITLE: EMILLYCHARLOTTE 2024/2025 ACADEMIC PERIOD
OWNER: EMILLYCHARLOTTE
COPYRIGHT STATEMENT: ©2024 EMILLYCHARLOTTE. ALL RIGHTS RESERVED
FIRST PUBLISHED: SEPTEMBER 2024
Nursing considerations for dronabinol (Marinol) - Answer✔️✔️-Teach the patient to
change positions slowly to prevent dizziness (orthostatic HTN). Most effective when
administered 1-3 hours before chemotherapy. Monitor the patient for hypotension,
hypertension, syncope, and tachycardia. Monitor liver function for increase.
What class is promethazine (Phenergan) - Answer✔️✔️-Phenothiazine-like Drugs
(Antiemetic)
What does promethazine (Phenergan) do? MOA - Answer✔️✔️-Competes with histamine
for receptor sites. This makes it effective at managing nausea and vomiting, but also
causes sedation because works on same sites as antihistamines, similar to Benadryl.
Nursing considerations for promethazine (Phenergan) - Answer✔️✔️-Effects on
laboratory values. May increase blood glucose levels. May decrease WBC, platelet, and
granulocyte counts. Teach patients to avoid. extensive sunlight exposure and to use
sunscreen . Monitor IV site closely if giving IV due to extravasation if infiltration occurs.
Teach patient to avoid alcohol while on this medication
Contraindications for promethazine (Phenergan) - Answer✔️✔️-Avoid giving with CNS
depressants and MAO inhibitors
What class is Busulfan, carboplatin, cisplatin - Answer✔️✔️-Alkylating Agents (Chemo)
What does Busulfan, carboplatin, cisplatin do? MOA - Answer✔️✔️-Interferes with DNA
production, causing cellular death. Nonspecific kills both cancerous & noncancerous
cells. CONTAINS PLATINUM
, TITLE: EMILLYCHARLOTTE 2024/2025 ACADEMIC PERIOD
OWNER: EMILLYCHARLOTTE
COPYRIGHT STATEMENT: ©2024 EMILLYCHARLOTTE. ALL RIGHTS RESERVED
FIRST PUBLISHED: SEPTEMBER 2024
Nursing considerations for Busulfan, carboplatin, cisplatin - Answer✔️✔️-Monitor lab
work, CBC with diff, Platelet, uric acid, kidney & liver function. Monitor: temperature &
respiratory status Assess neurological status. Contraindicated for patients with liver,
kidney & GI disorders. Do not use IVs or needles with aluminum for administration.
monitor fluid/nutritional intake from n/v
What class is Bleomycin, dactinomycin, doxorubicin, epirubicin - Answer✔️✔️-Antitumor
Antibiotics
What do you need to monitor when taking doxorubicin? - Answer✔️✔️-monitor closely bc
can cause secondary acute myeloid leukemia, cardiomyopathy, and myocardial toxicity
What kind of bottle does Antitumor medication come in? - Answer✔️✔️-Glass bottle
What does Bleomycin, dactinomycin, doxorubicin, epirubicin do? MOA - Answer✔️✔️-
Interferes with the production and action of nucleic acid to inhibit DNA & RNA replication
in cells which cause cellular death.
Nursing considerations for Bleomycin, dactinomycin, doxorubicin, epirubicin -
Answer✔️✔️-Monitor lab work:CBC with diff & BMP. Monitor Client:Cardiac, respiratory,
and neurological status.Monitor for bleeding, signs of infection, nutritional and fluid
intake. Contraindicated for patients with liver, kidney, cardiac, pulmonary and GI
disease. Close monitoring of IV site BC very caustic to vein.
What class is tamoxifen? - Answer✔️✔️-Selective Estrogen Receptor Modulator (SERM)
What does Tamoxifen treat? - Answer✔️✔️-breast cancer
