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PC 707 Pharm Final Exam Questions And Answers
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PC 707 Pharm Final Exam Questions AndAnswers 2024-2025
evidenced based prescribing resources - Answer Essential Evidence Plus, Dynamed
plus, Lexicomp, organizational guidelines, the Sanford guide to antimicrobial therapy
PLLR: Drugs in Pregnancy and Lactation: Improved Benefit-Risk information - Answer
assist health care providers in assessing benefit versus risk and in subsequent
counseling of pregnant women and nursing mothers who need to take medication, thus
allowing them to make informed and educated decisions for themselves and their
children.
Type 1 reaction - Answer IgE immune response Anaphylaxis
Type 2 Reaction- - Answer IgG immune reaction antibody-dependent cytotoxicity
Type 3 - Answer immune complex hypersensitivity
Type 4 - Answer Cell mediated delayed hypersensitivity Drug rash
Pseudo allergy - Answer probably mast cell degranulation by non-IgE medicate
mechanism
Absorption - Answer occurs in gi tract and small intestine
Distribution- -Answer The movement of the drug through the body after the drug is
absorbed, leaves the vascular system and is distributed to the site of action
, Metabolism- -Answer prepares the drug for excretion from the body
Protein bound- -Answer Bound drug is inactive, increase protein in the blood with cause
binding thus the need to increase dose
Excretion- -Answer elimination of the drug from the system
Agonist- Any drug that binds to a receptor and activates the receptor
Antagonist- Any drug the binds to a receptor and prevents the activation of the receptor
Partial agonist- binds and activates a given receptor but only partially activates
Enzyme inhibition- results in decrease cytochrome p450 enzymes and increase
pharmacological action of the drug
Enzyme induction --Increase the rate of metabolism of another drug
The World Health Organization WHO Six Step Model of Rational Prescribing --Answer 1.
Define the patient's problem
2. Specify the therapeutic objective
3. Select the treatment
4. Initiate the treatment
5. Instruct the patient
6. Monitor Effectiveness
Physiologic changes in the elderly Answer Significant changes that occur with aging
include increased gastric pH, slower peristalsis resulting in increased length of the time
for absorption to occur, decreased muscle mass and decreased total body water
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