Immunohematology Harr Exam Questions
With Correct Answers
What type of serological testing does the blood bank technologist perform when determining the
blood group of a patient?
A. Genotyping
B. Phenotyping
C. Both genotyping and phenotyping
D. Polymerase chain reaction - answer✔Correct Answer: B
If anti-K reacts 3+ with a donor cell with a genotype KK and 2+ with a Kk cell, the antibody is
demonstrating:
A. Dosage
B. Linkage disequilibrium
C. Homozygosity
D. Heterozygosity - answer✔Correct Answer: A
Carla expresses the blood group antigens Fya, Fyb, and Xga. James shows expressions of none
of these antigens. What factor(s) may account for the absence of these antigens in James?
A. Gender
B. Race
C. Gender and race
D. Medication - answer✔Correct Answer: C
Which of the following statements is true?
A. An individual with the BO genotype is homozygous for B antigen
B. An individual with the BB genotype is homozygous for B antigen
C. An individual with the OO genotype is heterozygous for O antigen
D. DCE/dCe - answer✔Correct Answer: A
Which genotype(s) will give rise to the Bombay phenotype?
A. HH only
B. HH and Hh
C. Hh and hh
D. hh only - answer✔Correct Answer: D
Meiosis in cell division is limited to the ova and sperm producing four gametes containing what
complement of DNA?
A. 1N
B. 2N
C. 3N
D. 4N - answer✔Correct Answer: A
A cell that is not actively dividing is said to be in:
A. Interphase
B. Prophase
C. Anaphase
D. Telophase - answer✔Correct Answer: A
Which of the following describes the expression of most blood group antigens?
A. Dominant
B. Recessive
C. Codominant
D. All are possible - answer✔Correct Answer: D
The alleged father of a child in a disputed case of paternity is blood group AB. The mother is
group O and the child is group O. What type of exclusion is this?
A. Direct/primary/first order
B. Probability
C. Random
D. Indirect/secondary/second order - answer✔Correct Answer: D
If the frequency of gene Y is 0.4 and the frequency of gene Z is 0.5, one would expect that they
should occur together 0.2 (20%) of the time. In actuality, they are found together 32% of the
time. This is an example of:
A. Crossing over
B. Linkage disequilibrium
C. Polymorphism
D. Chimerism - answer✔Correct Answer: B
In the Hardy-Weinberg formula, p2 represents:
A. The heterozygous population of one allele
B. The homozygous population of one allele
C. The recessive allele
D. The dominant allele - answer✔Correct Answer: B
In this type of inheritance, the father carries the trait on his X chromosome. He has no sons with
the trait because he passed his Y chromosome to his sons; however, all his daughters will express
the trait.
A. Autosomal dominant
B. Autosomal recessive
C. X-linked dominant
D. IgM antibodies are not limited by subclass specificity - answer✔Correct Answer: A
Which of the following enhancement mediums decreases the zeta potential, allowing antibody
and antigen to come closer together?
A. LISS
B. Polyethylene glycol
C. Polybrene
D. ZZAP - answer✔Correct Answer: A
This type of antibody response is analogous to an anamnestic antibody reaction.
A. Primary
B. Secondary
C. Tertiary
D. Anaphylactic - answer✔Correct Answer: B
Which antibodies to a component of complement are contained in the rabbit polyspecific
antihuman globulin reagent for detection of in vivo sensitization?
A. Anti-IgG and anti-C3a
B. Anti-IgG and anti-C3d
C. Anti-IgG and anti-IgM
D. All of these options - answer✔Correct Answer: B
Which of the following distinguishes A1 from A2 blood groups?
A. A2 antigen will not react with anti-A, A1 will
react strongly (4+)
B. An A2 person may form anti-A1; an A1 person
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