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Intro To Pharmacology With Complete Solutions
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Intro To Pharmacology With Complete Solutions
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Intro To Pharmacology With CompleteSolutions
Phases of Pharmacokinetics Answer: -Absorption
-Distribution
-Metabolism
-Excretion
Absorption Answer: -Transmission of medication from site of entry to the bloodstream
-Rate of absorption is how soon the medicine takes effect
-Amount of medication absorbed determines how strong the effect will be
-Route of administration affects both of these
Oral/ Enteral Medications Answer: Absorption Pattern
Varies widely because of:
-Stability and Solubility of the med
-GI pH and emptying time
-Any food in there?
-Other medications
-Forms of medicine (enteric coated, timed release, etc.)
Barriers to Absorption
-Must pass through the layer of epithelial cells that line the GI tract
Sublingual/ Buccal Answer: Sublingual - administered under the toungue
, Buccal - administered in the cheek area
Absorption Pattern
-Absorbs quickly through highly vascular mucous membrane
Barriers to Absorption
-Swallowing before its dissolved - gastric pH can inactivate medication
Suppositories Answer: Absorption Pattern
-Easily absorbed - local and systemic effects
Barriers to Absorption
-Presence of stool or infection can limit absorption
Inhalation Answer: Absorption Pattern
-Rapidly absorbed through alveolar capillary network
Barriers to Absorption
-Inspiratory effort - have to be able to inhale big
Topical/Intradermal Answer: Absorption Pattern
-Slow. Local and systemic effects depending on medication. Have to consider placement - fat tissue vs.
muscle.
Barriers to absorption
-Epidermal Cells Closely Packed - Tissue Quality - Infants skin creates enhanced absorption compared to
older kids and adults.
Intramuscular(in the muscle) Answer: Absorption Pattern
-Rate of absorption determined by:
----Solubility of medication in water
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