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Idiopathic Intracranial Hypertension Exam Questions And Accurate Answers
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Idiopathic Intracranial Hypertension Exam QuestionsAnd Accurate Answers
Idiopathic intracranial hypertension (pseudotumor cerebri) - Answer A neurological
condition characterized by an increase in CSF in the brain and spinal column which has
no underlying cause.
Risk factors for IIH - Answer Women, especially of childbearing age
Obesity or recent weight gain
Drugs/medications that increase risk for IIH - Answer Oral contraceptives
Growth hormones
Tetracycline
-Doxycycline (OD's use this often)
-Minocycline
Retinoids- Vit. A Isotretinoin (Accutane)
What are some of the drugs that may be associated with a possible link to IIH? - Answer
Lithium
Nalidixic acid
Withdrawal of steroids
What systemic disorders impede CSF flow that could result in IIH? - Answer Coagulation
disorders blocking the venous sinus
Venous sinus thrombosis- something gets stuck in the sinus blocking the flow.
These include SLE, which can result in hypercoagulation.
, polycistic ovary syndrome and IIH. -Answer a hormonal imbalance which involves
anovulation, amenorrhea, and infertility, many cysts
The hormonal imbalance can be a part of the IIH
What two disorders can result in low O2 and trigger IIH? -Answer Sleep apnea- failure to
have enough air while sleeping, hypoxic conditions.
Anemia
When the O2 is low in the CSF, the body responds to this by making more of, which in
turn raises the pressure.
IIH and Pregnancy The incidence of IIH tends to increase in pregnant females; possibly
due to the hormonal changes and a gain in weight, which may also affect several fluids
in the body.
Proposed mechanism of pathophysiology in IIH-Answer Decreased venous outflow or
excess production of CSF is considered the cause.
Estrogen may also play a role in this- It is not clear if it is due to an increase like growth
hormones or a decrease like when coming off of steroids
How does the composition of CSF compare to the blood? - Acellular, very little protein,
much less glucose.
Normal volumes for CSF?
For obese patients?
How often is it replaced? - 90-180 mm H20 (<200 mm is considered normal)
250 mm H20 in obese patients
Total volume is replaced every 5-7 hours
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