CPJE TOP 400 DRUGS & DOSES
QUESTIONS AND ANSWERS WITH
SOLUTIONS 2024
TylenolB-BANSWERBAcetaminophen
I:Bfever/pain
D:B325-650mg,BmaxB<B4000mg/dayBfromBallBsources
*ODB=BliverBdamage,BuseBNACBforBantidote
OfirmevB(IV)B-BANSWERBAcetaminophen
I:Bfever/pain
D:B<B4000mg/dayBfromBallBsources
*CanBtreatBmoreBsevereBpain
*ODB=BliverBdamage,BuseBNACBforBantidote
NACB-BANSWERBN-acetylcysteine
I:BAPAPBoverdose
BayerB-BANSWERBAspirin
I:Bfever/pain/inflammation
D:B81-325mgBqdB
CI:BpregnancyB(espB3rdBtrimester),BODB=BtinnitisB
*BBW:BCOX-1BselectivityBNSAIDB=BGIBbleed
Motrin,BAdvilB-BANSWERBIbuprofen
I:Bfever/pain/inflammation
Dose
-OTC:B200-400mgBqB4-6Bhrs
-Rx:B600-800BmgBtid,BmaxB3200mg/d
,*BBW:BCOX-1BselectivityBNSAIDB=BGIBbleed
NaprosynB-BANSWERBNaproxen,BAleve
I:Bfever/pain/inflammation
D:B
-OTC:B220mgBqd
-Rx:B250-550mgBbid
*HigherBGIBsideBeffects
*BBW:BCOX-1BselectivityBNSAIDB=BGIBbleed
DayproB-BANSWERBOxaprozin
I:Bfever/pain/inflammation
*SimilarBcautionBtoBpiroxicam:BhighBriskBforBGIBtoxBandBsevereBSJSB
*BBW:BCOX-1BselectivityBNSAIDB=BGIBbleed
VoltarenB-BANSWERBDiclofenacB(gel)
I:Bpain/inflammation
Dose:BAAAB2-4gBQID
ToradolB-BANSWERBKetorolac
I:Banalgesia
D:B
-IV/IMB30mgBxB1,BorB30mgBQIDB(maxB120mg/d)
-PO:B20mgBonceBafterBIVBorBIM,BthenB10mgBq4-6hrB(max:B40mg/d)
*MaxB=B5BdaysBofBtreatment
*MostBGIBtoxicBw/Bpiroxicam
*BBW:BCOX-1BselectivityBNSAIDB=BGIBbleed
IndocinB-BANSWERBIndomethacin
,-I:Bfever/pain/inflammation,Bgout
-D:B25-50mgBIR,B75mgBBIDBCR
*HighBriskBforBCNSBSEBandBGIBtoxicityB
*BBW:BCOX-1BselectivityBNSAIDB=BGIBbleed
ClinorilB-BANSWERBSulindac
*lessBcommonBNSAIDBthatBmayBbeBbetterBw/BreducedBrenalBfunction
*BBW:BCOX-1BselectivityBNSAIDB=BGIBbleed
RelafenB-BANSWERBNabumetone
I:Bfever/pain/inflammation
D:B1000-200mgBqdBorBbid
FeldeneB-BANSWERBPiroxicam
I:Bfever/pain/inflammation
D:B10-20mgBqd
*HighBriskBforBGIBtoxBandBsevereBSJS
*MostBGIBtoxicBw/Bketorolac
*BBW:BCOX-1BselectivityBNSAIDB=BGIBbleed
MobicB-BANSWERBMeloxicam
I:Bfever/pain/inflammation
D:B7.5-15mgBpoB(Max:B15mg/d)
*COX-2BselectivityBNSAID:BCVBeventB(MI,Bstroke)
CelebrexB-BANSWERBCelecoxib
I:Bfever/pain/inflammation
D:B200mgBqdBorBBID
*lowestBGIBbleedBriskBbutBhighestBCVBrisk
, *COX-2BselectivityBNSAID:BCVBeventB(MI,Bstroke)
HumiraB-BANSWERBAdalimumab
I:Barthritis,Bpsoriasis,BCrohn's,BUC,Betc
D:B40mgBSCBeveryBotherBweek
*BBW:BfatalBinfections,Bmalignancy,BTB
RemicadeB-BANSWERBInfliximab
I:Barthritis,Bpsoriasis,BCrohn's,BUC,Betc
D:B3Bmg/kgBIVBonBweeksB0,B2BandB6,BthenBq8w
*DelayedBhypersensitivityBreactions
*BBW:BfatalBinfections,Bmalignancy,BTB
EnbrelB-BANSWERBEtanercept
I:Barthritis,Bpsoriasis,BCrohn's,BUC,Betc
D:B50mgBSCBweekly
*BBW:BfatalBinfections,Bmalignancy,BTB
OrenciaB-BANSWERBAbatacept
I:Barthritis
D:B500-1000mgBIVBatB0,B2BandB4Bweeks,BthenBqm,B125mgBSCBweekly
*NSBonly
*Warnings:Bmalignancies,BseriousBinfections,BmayBworsenBCOPDBsx
KineretB-BANSWERBAnakinra
I:BRA
D:B100mgBSCBqd
*Warnings:Bmalignancies,BseriousBinfections