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UST ABSN Pathopharmacology 1 Questions & 100% Correct Answers

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How do you define the word drug? ~~> A drug is any chemical that can affect living processes Define pharmacology ~~> Pharmacology can be defined as the study of drugs and their interaction with living things Define clinical pharmacology ~~> study of effect of drugs in man (as com...

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  • September 13, 2024
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1 | P a g e | © copyright 2024/2025 | Grade A+




UST ABSN Pathopharmacology 1
Questions & 100% Correct Answers
How do you define the word drug?

✓ ~~> A drug is any chemical that can affect living processes




Define pharmacology

✓ ~~> Pharmacology can be defined as the study of drugs and their

interaction with living things




Define clinical pharmacology

✓ ~~> study of effect of drugs in man (as compared to animals or

comparative pharmacology




what are pharmacotherapeutics?

✓ ~~> also known as therapeutics, pharmacotherapeutics emphasizes

the disease state and its characteristics including therapy for and use

of drugs in prevention and treatment of condition




what are chemotherapeutic agents?




Master01 | September, 2024/2025 | Latest update

, 2 | P a g e | © copyright 2024/2025 | Grade A+



✓ ~~> Drugs used to destroy or eliminate pathogenic cells or organisms.

The term is usually restricted to anti-infectives and cancer

chemotherapy.




what is toxicology and how do we measure a drugs toxicity?

✓ ~~> Toxicology deals with the effects of drugs. Toxicity is measured

through the Therapeutic Index.




What is the therapeutic index?

✓ ~~> therapeutic index is a ratio that measures toxicity. The ratio is

found by putting the dose *capable of killing 50% of animals (LD50)

over than required to acheive a beneficial effect in 50% of animals

(ED50).




In clinical practice the THERAPEUTIC INDEX is described as the ratio of the

dose that causes toxicity over the dose that provides therapeutic effect.




what is tolerance?

✓ ~~> Tolerance is the hyporeactivity that occurring from chronic

exposure to a drug. Achievement of the same effects of the drug

requires larger and larger doses.




Master01 | September, 2024/2025 | Latest update

, 3 | P a g e | © copyright 2024/2025 | Grade A+



What is cross tolerance and how does it occur?

✓ ~~> Cross tolerance may happen when tolerance occurs across

drugs of the same class or across drugs that have the same

pharmacological effects




what are some examples of neurological adaptation/ cellular tolerance to

drugs?

✓ ~~> Tolerance to opioids, barbiturates, and alcohol




What is metabolic drug tolerance?

✓ ~~> metabolic drug tolerance occurs when the body has an

increased rate of elimination of the drug.




what is the most common form of metabolic tolerance?

✓ ~~> enzyme induction which occurs when there is an increased

activity of enzymes (the drug transport system)




What is pharmacodynamics?

✓ ~~> pharmacodynamic processes determine the nature and intensity

of the response. It is essentially the effect of the drug ON the body.




Master01 | September, 2024/2025 | Latest update

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