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NUR 283 Transition To Registered Nursing Practice Pharmacology_Exam_2 Review with Verified Solutions
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NUR 283 Transition To Registered Nursing Practice

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  • September 13, 2024
  • 7
  • 2024/2025
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PHARMACOLOGY EXAM 2
Unit 4 –

Adrenergic Agonists

Epinephrine “Epi-Pen” - Think running from a bear’

 Nonselective – Stimulate Alpha, beta 1 and 2
 Given for: Allergic reaction, cardiac arrest
 Stimulate the sympathetic nervous system
 Dilated lungs and pupils
 Receptors
 Alpha “Arteries” – vasoconstriction
 Beta 1 “One Heart” – Increase Heart rate
 Beta 2 “Two Lungs” Bronchi dilatation, liver glycogenolysis (increases blood sugar)
 Epi Pen Teaching – Know it!
 5-10 secs, CAN massage site, outer thigh subQ, go to ER after use
 Atropine for low heart rate
 Adverse – cardiac dysrhythmias
 Side Effect – Low blood glucose (expected)




Adrenergic Blockers

Atenolol (More selective for Beta 1) A-M Medications

Contraindicators – Heat Block, Bradycardia

 Given for: Antihypertensive, Reynaud’s, BPH
 Beta Blocker – Heart and Lungs
 Constricts lungs – no COPD Patient (But beta 1 would be safer to give to lung patient)
 Heart Rate low! Below 60
 Orthostatic Hypotension – Safety
 Always take at same time a day/ Several Weeks to work/ do not drive
 Do not stop Abruptly – Rebound Hypertension



Cholinergic Agonist “Think of colon”
Wet & Moist & Mucousy

 Constricts pupils, increase secretion, runny eyes, do not give to Gerd/Ulcers, loss stool/diarrhea

Bethanechol Chloride – Decreases BP



This study source was downloaded by 100000890074950 from CourseHero.com on 09-12-2024 21:44:03 GMT -05:00


https://www.coursehero.com/file/234564910/Pharmacology-Exam-2-AutoRecovered-AutoRecovereddocx/

, Pilocarpine- Tx for glaucoma

The outflow of aqueous humor in the eyes is increased




Anti Cholinergic – Dry up

 Patient working out and not sweating – overheated
 Exact opposite of above
 Decrease secretions
 Tolterodine Tartrate – for overactive bladder, not given for pulse (can increase) , decrease in
urination (TT no more )


*Other Notes in Pharm Book*


UNIT 5

Parkinson’s Disease
 Not enough dopamine, too much acetylcholine

Carbidopa-Levodopa

Carbidopa disguises levodopa to get into blood brain barrier

This drug improves nerve impulse transmission in the brain
 Side Effects – GI Distress, dry mouth, Dark Urine, Orthostatic Hypotension
 Adverse Reactions- Palpitations, hypotension, Urinary retention, Psychosis, Severe depression
 Contraindications- Antipsychotics
 Contact PCP if undergoing glaucoma treatment
 Do not take with high protein foods, Vitamin B-6 it will decrease absorption



COMT Inhibitors

Tolcapone – Adjunct to Parkinson’s!

 Inhibits COMT because it inactivates dopamine, usually given with Levodopa
 Not given alone (Adjunct) Prolongs Levodopa action
 Monitor LFT, AST ALT, Hepatotoxic Monitor Liver
 Assessment – Vitals orthostatic hypertension, S/S of Parkinson’s, Med Hx
 Avoid high protein foods
 Monitor for Suicidal ideation


This study source was downloaded by 100000890074950 from CourseHero.com on 09-12-2024 21:44:03 GMT -05:00


https://www.coursehero.com/file/234564910/Pharmacology-Exam-2-AutoRecovered-AutoRecovereddocx/

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