100% satisfaction guarantee Immediately available after payment Both online and in PDF No strings attached
logo-home
Exam 1 Nura 221 COX inhibitors and Opioids Bellarmine Questions & 100% Correct Answers $12.49   Add to cart

Exam (elaborations)

Exam 1 Nura 221 COX inhibitors and Opioids Bellarmine Questions & 100% Correct Answers

 4 views  0 purchase
  • Course
  • Nura 221 COX
  • Institution
  • Nura 221 COX

COX ~~> cyclo-oxygenase an important enzyme in the synthesis of prostaglandin Cox is found in all tissues and helps regulate many processes COX inhibitors ~~> NSAIDs (Non-Steroidal Anti-Inflammatory Medications) and selective COX2 inhibitors COX-1 (5 things) ~~> *This is the ...

[Show more]

Preview 3 out of 28  pages

  • September 12, 2024
  • 28
  • 2024/2025
  • Exam (elaborations)
  • Questions & answers
  • Nura 221 COX
  • Nura 221 COX
avatar-seller
ExamArsenal
1 | P a g e | © copyright 2024/2025 | Grade A+




Exam 1 Nura 221 COX inhibitors and
Opioids Bellarmine Questions & 100%
Correct Answers
COX

✓ ~~> cyclo-oxygenase




an important enzyme in the synthesis of prostaglandin

Cox is found in all tissues and helps regulate many processes




COX inhibitors

✓ ~~> NSAIDs (Non-Steroidal Anti-Inflammatory Medications)

and selective COX2 inhibitors




COX-1 (5 things)

✓ ~~> *This is the protective cox and is located in all tissues




1. Protects the gastric area by reducing secretion of gastric acid




2. Increasing secretion of bicarbonate and cytoprotective mucus




Master01 | September, 2024/2025 | Latest update

, 2 | P a g e | © copyright 2024/2025 | Grade A+



3.Maintenance of sub-mucosal blood flow




4. Catalyzes synthesis of PGE2 and PGI2 which promote vasodilation and

therefore increased renal blood flow




5. Promotes synthesis of TXA2 (which stimulates platelet aggregation, which

can be a negative event) in positive way it can clot (stop bleeding) a cut




COX-2

✓ ~~> *reactive cox

This is present only at the site of tissue injury and the brain




When activated it:

Causes inflammation

Causes pain

Causes fever (increased heat at site of injury)




Two types of COX

✓ ~~> COX-1

COX-2



Master01 | September, 2024/2025 | Latest update

, 3 | P a g e | © copyright 2024/2025 | Grade A+




Examples of NSAIDs

✓ ~~> - Ibuprofen (Advil/Motrin)

- Naproxen & Naproxen Sodium (Naprosyn & Aleve)

- Aspirin

- Indomethacin (Indocin)

- Ketorolac (Toradol)




3 primary functions of NSAIDS

✓ ~~> •Suppression of inflammation

•Relief of pain (analgesic)

•Reduction of fever (anti-pyretic)




Two types of Cox inhibitors

✓ ~~> specific and non-specific




What are non-specific cox inhibitors?

✓ ~~> NSAID that blocks the action of cox1 and cox2




also called First-generation



Master01 | September, 2024/2025 | Latest update

The benefits of buying summaries with Stuvia:

Guaranteed quality through customer reviews

Guaranteed quality through customer reviews

Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.

Quick and easy check-out

Quick and easy check-out

You can quickly pay through credit card or Stuvia-credit for the summaries. There is no membership needed.

Focus on what matters

Focus on what matters

Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!

Frequently asked questions

What do I get when I buy this document?

You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.

Satisfaction guarantee: how does it work?

Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.

Who am I buying these notes from?

Stuvia is a marketplace, so you are not buying this document from us, but from seller ExamArsenal. Stuvia facilitates payment to the seller.

Will I be stuck with a subscription?

No, you only buy these notes for $12.49. You're not tied to anything after your purchase.

Can Stuvia be trusted?

4.6 stars on Google & Trustpilot (+1000 reviews)

71498 documents were sold in the last 30 days

Founded in 2010, the go-to place to buy study notes for 14 years now

Start selling
$12.49
  • (0)
  Add to cart