Red Blood Cells
What accounts of 99.9 percent of formed components of blood? - ANS RBC
What is the red pigment in blood? - ANS Hemoglobin
What percentage of plasma is water? - ANS 92 percent
What percent of plasma is protein? - ANS 7 percent
What makes up approximately 1/3 of all cells in the body? - ANS RBC
What is the red blood cell count for men? - ANS 4.5 - 6.3 million/mcL
What is the red blood cell count for women? - ANS 4.2 - 5.5 million/mcL
How many RBCs are in a single drop of blood? - ANS 260 million
How many RBCs are in the blood of an average adult? - ANS 25 trillion
Biconcave disc with a thin central region and a thicker outer margin - ANS RBC
What effect does the shape of RBC have on function? - ANS - Large
surface-area-to-volume ratio
- Enables stacking
- Enables bending and flexing
How does the large surface area of blood cells affect their function? - ANS The
greater the surface area per unit volume, the faster the exchange between interior
of the cell and the surrounding plasma
What is the total surface are of RBCs in an average adult? - ANS About 3800
square meters
Stacks of RBCs - ANS Rouleaux
, How does rouleaux improve the function of RBCs? - ANS Smooth the flow
through narrow blood vessels
Cells that lose most of their organelles, including their nuclei, during
differentiation - ANS RBC
What is the lifespan of a RBC? - ANS 120 days
Why is the lifespan of RBC short? - ANS They cannot divide or synthesize
structural proteins due to a lack of organelles, so they cannot perform repairs
What type of metabolism is used by RBC? - ANS Anaerobic
Have no nuclei, ribosomes, or mitochondria. Retain only cytoskeleton - ANS RBC
What makes up 95 percent of RBC intracellular proteins? - ANS Hemoglobin
Normal Hgb in males - ANS 14 - 18 g/dL
Normal Hgb in females - ANS 12 - 16 g/dL
Have complex quaternary structure - ANS Hgb
Contains two alpha and two beta chains of polypeptides that are globular protein
subunits - ANS Hgb
What do the chains in Hgb resemble? - ANS Myoglobin
What is found within each Hgb chain? - ANS Heme
Nonprotein pigment complex that holds an iron ion - ANS Heme
Oxygen bound to Hgb - ANS Oxyhemoglobin
HbO2 - ANS Oxyhemoglobin
Unbound Hgb - ANS Deoxyhemoglobin
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